node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDR73170.1 | SDR77972.1 | SAMN04489717_0304 | SAMN04489717_0528 | Fructose-bisphosphate aldolase, class II. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.849 |
SDR73170.1 | SDS95678.1 | SAMN04489717_0304 | SAMN04489717_4487 | Fructose-bisphosphate aldolase, class II. | Phosphoglucomutase. | 0.843 |
SDR73170.1 | SDS96195.1 | SAMN04489717_0304 | SAMN04489717_4506 | Fructose-bisphosphate aldolase, class II. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.973 |
SDR73170.1 | SDT02233.1 | SAMN04489717_0304 | SAMN04489717_4737 | Fructose-bisphosphate aldolase, class II. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.920 |
SDR73170.1 | SDT10129.1 | SAMN04489717_0304 | SAMN04489717_5034 | Fructose-bisphosphate aldolase, class II. | Transketolase; Belongs to the transketolase family. | 0.843 |
SDR73170.1 | SDT10169.1 | SAMN04489717_0304 | SAMN04489717_5036 | Fructose-bisphosphate aldolase, class II. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.962 |
SDR73170.1 | pfp | SAMN04489717_0304 | SAMN04489717_4853 | Fructose-bisphosphate aldolase, class II. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.893 |
SDR73170.1 | tal | SAMN04489717_0304 | SAMN04489717_5035 | Fructose-bisphosphate aldolase, class II. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.909 |
SDR73170.1 | tpiA | SAMN04489717_0304 | SAMN04489717_4504 | Fructose-bisphosphate aldolase, class II. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.974 |
SDR73170.1 | zwf-2 | SAMN04489717_0304 | SAMN04489717_5037 | Fructose-bisphosphate aldolase, class II. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.741 |
SDR77972.1 | SDR73170.1 | SAMN04489717_0528 | SAMN04489717_0304 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase, class II. | 0.849 |
SDR77972.1 | SDS95678.1 | SAMN04489717_0528 | SAMN04489717_4487 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglucomutase. | 0.843 |
SDR77972.1 | SDS96195.1 | SAMN04489717_0528 | SAMN04489717_4506 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.993 |
SDR77972.1 | SDT02233.1 | SAMN04489717_0528 | SAMN04489717_4737 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.958 |
SDR77972.1 | SDT10129.1 | SAMN04489717_0528 | SAMN04489717_5034 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; Belongs to the transketolase family. | 0.886 |
SDR77972.1 | SDT10169.1 | SAMN04489717_0528 | SAMN04489717_5036 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.969 |
SDR77972.1 | pfp | SAMN04489717_0528 | SAMN04489717_4853 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.976 |
SDR77972.1 | tal | SAMN04489717_0528 | SAMN04489717_5035 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.961 |
SDR77972.1 | tpiA | SAMN04489717_0528 | SAMN04489717_4504 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.995 |
SDR77972.1 | zwf-2 | SAMN04489717_0528 | SAMN04489717_5037 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.757 |