STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT14356.15-oxoprolinase (ATP-hydrolysing). (1241 aa)    
Predicted Functional Partners:
SDT02413.1
Glutamate synthase (NADH) large subunit.
    
 0.921
SDS53417.1
Glutamate dehydrogenase.
  
  
  0.859
SDS24584.1
L-proline dehydrogenase.
    
  0.849
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
    
  0.843
SDS49587.1
AIG2-like family protein.
    
  0.842
SDS99877.1
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
   
 
  0.839
SDS09071.1
Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.825
SDS03242.1
Valine dehydrogenase (NAD+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.811
SDS73543.1
Thioredoxin reductase (NADPH).
    
  0.781
SDS16664.1
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases.
    
  0.769
Your Current Organism:
Actinopolymorpha singaporensis
NCBI taxonomy Id: 117157
Other names: A. singaporensis, Actinopolymorpha singaporensis Wang et al. 2001 emend. Nouioui et al. 2018, Actinosingapura polymorpha, DSM 22024, JCM 10761, NBRC 100040, NRRL B-24113, strain IM 7744
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