STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY92679.1PFAM: Protein of unknown function, DUF393. (166 aa)    
Predicted Functional Partners:
topA-2
DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...]
 
     0.682
AFY94947.1
Putative membrane protein; PFAM: Protein of unknown function (DUF1517).
  
     0.633
AFY95572.1
PsbP; PFAM: PsbP.
  
     0.557
AFY96208.1
Hypothetical protein.
  
     0.557
AFY93207.1
Chlorophyllase.
  
     0.505
AFY92678.1
Hypothetical protein.
       0.461
psbM
Photosystem II reaction center protein PsbM; One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface.
  
     0.454
AFY95836.1
PFAM: Protein of unknown function (DUF1092).
  
     0.446
AFY95151.1
PFAM: Uncharacterized integral membrane protein (DUF2301).
  
     0.444
AFY92682.1
Hypothetical protein.
       0.430
Your Current Organism:
Chamaesiphon minutus
NCBI taxonomy Id: 1173020
Other names: C. minutus PCC 6605, Chamaesiphon minutus PCC 6605, Chamaesiphon sp. ACMM 446, Chamaesiphon sp. ATCC 27169, Chamaesiphon sp. PCC 6605
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