STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ11837.15'-nucleotidase, exopolyphosphatase, 3'-nucleotidase; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: npu:Npun_R1763 stationary phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: Stationary-phase survival protein SurE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase. (229 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.945
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
    
 0.939
panC/cmk
Pantothenate synthetase, cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
    
 0.932
surE
5'-nucleotidase, exopolyphosphatase, 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
 
0.924
AFZ14912.1
PFAM: IMP dehydrogenase / GMP reductase domain; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR005992:IPR001093; KEGG: ana:alr0051 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; SPTR: IMP dehydrogenase; TIGRFAM: IMP dehydrogenase-related 2.
    
 0.924
purH
PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: AICARFT/IMPCHase bienzyme; InterPro IPR011607:IPR013982:IPR002695; KEGG: npu:Npun_R6316 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AIC [...]
     
 0.919
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.919
AFZ12124.1
PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR019468; KEGG: cyh:Cyan8802_2587 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.917
AFZ11134.1
Competence/damage-inducible protein cinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008135:IPR008136; KEGG: ava:Ava_2078 competence damage-inducible protein A; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competen [...]
    
  0.915
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.913
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
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