STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ11981.1Cobalamin synthesis protein P47K; PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR011629:IPR003495; KEGG: ana:all4722 hypothetical protein; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal; SMART: Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal; SPTR: Putative uncharacterized protein; manually curated. (347 aa)    
Predicted Functional Partners:
AFZ11982.1
PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: ana:all4725 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; manually curated.
     
 0.768
rpsN
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.557
AFZ11983.1
Hypothetical protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG2072 flavoprotein involved in K+ transport; KEGG: cyn:Cyan7425_1918 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.519
AFZ13336.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR000878:IPR012818:IPR014008; KEGG: cyc:PCC7424_5061 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase, CbiE subunit domain protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, [...]
     
 0.461
AFZ15004.1
Precorrin-3 methyltransferase; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR002750:IPR000878; KEGG: ter:Tery_4366 precorrin-3 methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core.
     
 0.447
rpmB
PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; COGs: COG0227 Ribosomal protein L28; HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: cyc:PCC7424_2853 ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.429
hisI
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR008179:IPR002496:IPR021130:IPR023019; KEGG: ana:all3263 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diph [...]
     
 0.416
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.