STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ13982.1PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141:IPR004013:IPR011708:IPR004365:IPR 004805; KEGG: cyn:Cyan7425_4334 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit. (1225 aa)    
Predicted Functional Partners:
AFZ11010.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.998
AFZ13110.1
TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ana:all4705 DNA polymerase III subunit delta'; SPTR: All4705 protein; TIGRFAM: DNA polymerase III, delta prime subunit.
    
 0.997
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.988
AFZ11390.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: cyc:PCC7424_5666 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: Putative DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 0.988
dnaX-2
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.988
AFZ13333.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: cyh:Cyan8802_4220 DNA polymerase III subunit delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 0.988
AFZ14147.1
PFAM: Single-strand binding protein family; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: cyt:cce_2001 single-stranded DNA-binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding.
   
 
 0.878
AFZ14606.1
PFAM: Single-strand binding protein family; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: cyn:Cyan7425_1502 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding.
   
 
 0.878
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.673
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
   
 0.649
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
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