STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (324 aa)    
Predicted Functional Partners:
AFZ14729.1
Adenosylcobinamide-phosphate guanylyltransferase, adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: cyh:Cyan8802_1571 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase.
 
 
 0.991
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.991
AFZ14698.1
PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Cob(I)alamin adenosyltransferase N terminal; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: cyh:Cyan8802_3572 cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR.
 
  
 0.973
AFZ15416.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: npu:Npun_F2523 cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
  
 0.968
AFZ13380.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: cyn:Cyan7425_3792 hypothetical protein; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; SPTR: Putative Cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
  
 0.956
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
 0.910
AFZ13336.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR000878:IPR012818:IPR014008; KEGG: cyc:PCC7424_5061 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase, CbiE subunit domain protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, [...]
 
  
 0.901
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.901
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.900
AFZ13335.1
PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: cyp:PCC8801_1477 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SPTR: Precorrin-8X methylmutase subfamily.
 
  
 0.886
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
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