STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
AFZ15149.1Diguanylate cyclase with PAS/PAC and Chase2 sensors; PFAM: GGDEF domain; CHASE2 domain; PAS fold; COGs: COG4252 transmembrane sensor domain; InterPro IPR000014:IPR000160:IPR007890:IPR013656; KEGG: ana:all1219 hypothetical protein; PFAM: CHASE2; PAS fold-4; Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS; manually curated. (718 aa)    
Predicted Functional Partners:
AFZ14505.1
Diguanylate phosphodiesterase; PFAM: EAL domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: ava:Ava_0828 diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: Diguanylate phosphodiesterase, EAL domain; SMART: Diguanylate phosphodiesterase, EAL domain; SPTR: Diguanylate cyclase/phosphodiesterase with GAF sensor.
  
 0.865
AFZ14523.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: Histidine kinase response regulator hybrid p [...]
    
 0.836
AFZ12158.1
Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR003607:IPR006674; KEGG: ava:Ava_1777 metal dependent phosphohydrolase, HD region with response regulator receiver modulation; PFAM: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD subdomain; SMART: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD domain; SPTR: [...]
    0.832
AFZ12724.1
Putative integral membrane sensor protein; PFAM: Stage II sporulation protein E (SpoIIE); Bacterial signalling protein N terminal repeat; COGs: COG3300 MHYT domain (predicted integral membrane sensor domain); InterPro IPR005330:IPR010822:IPR001932; KEGG: cyn:Cyan7425_2801 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; MHYT; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase.
 
  
 0.801
AFZ12610.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Bacterial signalling protein N terminal repeat; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3300 MHYT domain (predicted integral membrane sensor domain); InterProIPR005330:IPR013655:IPR013656:IPR003018:IPR 003661:IPR003594:IPR001789:IPR000014:IPR001610; KEGG: npu:Npun_R3691 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; MHYT; PAS fold-4; GAF; Signal transduction histidine kinase, subgroup 1, dim [...]
 
 0.748
AFZ12609.1
PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: npu:Npun_F5361 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction res [...]
 
  
0.734
AFZ14522.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001789:IPR001633; KEGG: cyc:PCC7424_2022 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, EAL domain; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Cyclic diguanylate phosphodiesterase (EAL) domain protein; TIGRFAM: Di [...]
 
  
0.733
AFZ14880.1
WD40 repeat-containing protein; PFAM: WD domain, G-beta repeat; COGs: COG2319 FOG: WD40 repeat; InterPro IPR019781:IPR001680; KEGG: ava:Ava_1624 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD-40 repeat protein.
      0.731
AFZ15109.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR001789:IPR000014:IPR001610:IPR000160:IPR 001633:IPR013655; KEGG: cyc:PCC7424_0596 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; PAS fold-3; SMART: Digu [...]
 
 
0.716
AFZ15410.1
PFAM: Stage II sporulation protein E (SpoIIE); InterPro IPR001932:IPR010822; KEGG: npu:Npun_R2264 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-like; SPTR: Putative anti-sigma regulatory factor,serine/threonine protein kinase.
  
 
 0.715
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
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