STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ31609.1Cyclase/dehydrase; PFAM: Polyketide cyclase / dehydrase and lipid transport; COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: npu:Npun_R6238 cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; SPTR: Cyclase/dehydrase. (235 aa)    
Predicted Functional Partners:
AFZ31608.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: npu:Npun_R6237 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; PRIAM: S-(hydroxymethyl)glutathione dehydrogenase; SPTR: Alcohol dehydrogenase.
 
    0.890
AFZ31607.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: ana:alr0897 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; SPTR: Alcohol dehydrogenase.
 
    0.855
AFZ32929.1
Cyclase/dehydrase; PFAM: Polyketide cyclase / dehydrase and lipid transport; COGs: COG5637 integral membrane protein; InterPro IPR005031; KEGG: npu:Npun_R0497 cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; SPTR: Streptomyces cyclase/dehydrase.
  
     0.668
AFZ31610.1
PFAM: DJ-1/PfpI family; Domain of unknown function (DUF2383); TIGRFAM: intracellular protease, PfpI family; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR006286:IPR002818; KEGG: ava:Ava_4496 peptidase C56, PfpI; PFAM: ThiJ/PfpI; SPTR: Peptidase C56, PfpI; TIGRFAM: Peptidase C56, PfpI.
 
    0.624
AFZ30788.1
PFAM: Predicted membrane protein (DUF2231); COGs: COG4244 membrane protein; KEGG: naz:Aazo_1488 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.619
AFZ31606.1
PFAM: Cupin domain; InterPro IPR013096; KEGG: ana:alr0898 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Alr0898 protein.
 
     0.526
AFZ32939.1
3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: cyn:Cyan7425_0579 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.470
AFZ31472.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198; KEGG: cyc:PCC7424_5076 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
  
     0.461
AFZ33020.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR001789:IPR 000014:IPR001610:IPR013656:IPR013655:IPR013767; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold-4; [...]
  
     0.450
AFZ31249.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: cyn:Cyan7425_4611 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-b [...]
  
     0.447
Your Current Organism:
Gloeocapsa sp. PCC7428
NCBI taxonomy Id: 1173026
Other names: Chroococcus sp. Cey un, G. sp. PCC 7428, Gloeocapsa sp. ATCC 29159, Gloeocapsa sp. PCC 7428
Server load: low (24%) [HD]
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