A0A0J9X5F6 protein (Geotrichum candidum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A0J9X5F6

annotation not available (822 aa)

Predicted Functional Partners:

A0A0J9X6T4

0.985

A0A0J9XHH9

0.874

A0A0J9XLH6

0.833

A0A0J9XC19

0.768

A0A0J9XA13

0.736

A0A0J9XG25

0.736

A0A0J9XEA5

0.733

A0A0J9X2U5

0.683

A0A0J9XDB0

0.670

A0A0J9X658

0.624

Your Current Organism:

Geotrichum candidum

NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J9X2U5	A0A0J9X5F6	annotation not available	annotation not available	0.683
A0A0J9X2U5	A0A0J9X6T4	annotation not available	annotation not available	0.658
A0A0J9X2U5	A0A0J9XA13	annotation not available	annotation not available	0.493
A0A0J9X2U5	A0A0J9XC19	annotation not available	Belongs to the AAA ATPase family.	0.665
A0A0J9X2U5	A0A0J9XDB0	annotation not available	annotation not available	0.651
A0A0J9X2U5	A0A0J9XG25	annotation not available	annotation not available	0.493
A0A0J9X2U5	A0A0J9XHH9	annotation not available	annotation not available	0.822
A0A0J9X2U5	A0A0J9XLH6	annotation not available	annotation not available	0.988
A0A0J9X5F6	A0A0J9X2U5	annotation not available	annotation not available	0.683
A0A0J9X5F6	A0A0J9X658	annotation not available	annotation not available	0.624
A0A0J9X5F6	A0A0J9X6T4	annotation not available	annotation not available	0.985
A0A0J9X5F6	A0A0J9XA13	annotation not available	annotation not available	0.736
A0A0J9X5F6	A0A0J9XC19	annotation not available	Belongs to the AAA ATPase family.	0.768
A0A0J9X5F6	A0A0J9XDB0	annotation not available	annotation not available	0.670
A0A0J9X5F6	A0A0J9XEA5	annotation not available	annotation not available	0.733
A0A0J9X5F6	A0A0J9XG25	annotation not available	annotation not available	0.736
A0A0J9X5F6	A0A0J9XHH9	annotation not available	annotation not available	0.874
A0A0J9X5F6	A0A0J9XLH6	annotation not available	annotation not available	0.833
A0A0J9X658	A0A0J9X5F6	annotation not available	annotation not available	0.624
A0A0J9X658	A0A0J9X6T4	annotation not available	annotation not available	0.999

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.631

expected number of edges:

21

PPI enrichment p-value:

0.00195

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 44

1.63

2.89

2.49e-09

GO:0009056

Catabolic process

9 of 136

1.19

1.57

1.11e-07

GO:0044270

Cellular nitrogen compound catabolic process

3 of 29

1.38

0.75

0.0230

GO:0046700

Heterocycle catabolic process

3 of 32

1.34

0.7

0.0278

GO:0044281

Small molecule metabolic process

11 of 523

0.69

0.65

6.89e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051537

2 iron, 2 sulfur cluster binding

4 of 9

2.02

2.05

7.01e-05

GO:0071949

FAD binding

3 of 6

2.07

1.57

0.00089

GO:0016491

Oxidoreductase activity

8 of 247

0.88

0.78

0.00029

GO:0043167

Ion binding

9 of 681

0.49

0.33

0.0247

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2554

Aromatic compound catabolic process

8 of 16

2.07

4.97

1.35e-12

CL:2556

CO dehydrogenase flavoprotein, C-terminal, and Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

6 of 7

2.3

4.57

3.52e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

4 of 90

1.02

0.59

0.0257

map01120

Microbial metabolism in diverse environments

6 of 236

0.78

0.48

0.0225

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01799

[2Fe-2S] binding domain

3 of 3

2.37

1.77

0.00047

PF00941

FAD binding domain in molybdopterin dehydrogenase

3 of 3

2.37

1.77

0.00047

PF00111

2Fe-2S iron-sulfur cluster binding domain

3 of 5

2.15

1.72

0.00047

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036683

CO dehydrogenase flavoprotein, C-terminal domain superfamily

4 of 4

2.37

2.53

1.44e-05

IPR005107

CO dehydrogenase flavoprotein, C-terminal

4 of 4

2.37

2.53

1.44e-05

IPR036884

[2Fe-2S]-binding domain superfamily

3 of 3

2.37

1.79

0.00044

IPR002888

[2Fe-2S]-binding

3 of 3

2.37

1.79

0.00044

IPR002346

Molybdopterin dehydrogenase, FAD-binding

3 of 3

2.37

1.79

0.00044

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01092

CO dehydrogenase flavoprotein C-terminal domain

3 of 3

2.37

2.07

0.00012

SM01008

Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

2 of 5

1.97

0.92

0.0177

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