STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0J9X609Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (594 aa)    
Predicted Functional Partners:
A0A0J9X9S4
Similar to Saccharomyces cerevisiae YDL171C GLT1 NAD(+)-dependent glutamate synthase (GOGAT).
  
 
 0.753
A0A0J9XJ06
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 
 0.721
A0A0J9X5D2
Thioredoxin reductase.
    
 0.706
A0A0J9XCQ3
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 0.696
A0A0J9XJ55
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 0.696
A0A0J9X7D2
Histidine biosynthesis trifunctional protein.
  
 
 0.690
A0A0J9XF60
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.690
A0A0J9YHC0
Amidophosphoribosyltransferase.
    
 0.685
A0A0J9XGV8
Similar to Saccharomyces cerevisiae YMR217W GUA1 GMP synthase.
    
 0.682
A0A0J9X392
Similar to Saccharomyces cerevisiae YPR145W ASN1 Asparagine synthetase.
  
 
 0.675
Your Current Organism:
Geotrichum candidum
NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis
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