A0A0J9X8D1 protein (Geotrichum candidum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A0J9X8D1

annotation not available (266 aa)

Predicted Functional Partners:

A0A0J9X527

0.832

A0A0J9X6Z5

0.829

A0A0J9X3Z5

0.825

A0A0J9X8U9

0.825

A0A0J9XEY0

0.819

A0A0J9XAL2

0.810

A0A0J9XLD6

0.810

A0A0J9X9Q2

0.805

A0A0J9XIE1

0.803

A0A0J9XAR9

0.801

Your Current Organism:

Geotrichum candidum

NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J9X3Z5	A0A0J9X527	annotation not available	annotation not available	0.956
A0A0J9X3Z5	A0A0J9X6Z5	annotation not available	Belongs to the universal ribosomal protein uL16 family.	0.998
A0A0J9X3Z5	A0A0J9X8D1	annotation not available	annotation not available	0.825
A0A0J9X3Z5	A0A0J9X8U9	annotation not available	Belongs to the universal ribosomal protein uS2 family.	0.998
A0A0J9X3Z5	A0A0J9X9Q2	annotation not available	Belongs to the universal ribosomal protein uS5 family.	0.997
A0A0J9X3Z5	A0A0J9XAL2	annotation not available	annotation not available	0.999
A0A0J9X3Z5	A0A0J9XAR9	annotation not available	annotation not available	0.989
A0A0J9X3Z5	A0A0J9XEY0	annotation not available	annotation not available	0.991
A0A0J9X3Z5	A0A0J9XIE1	annotation not available	annotation not available	0.995
A0A0J9X3Z5	A0A0J9XLD6	annotation not available	annotation not available	0.997
A0A0J9X527	A0A0J9X3Z5	annotation not available	annotation not available	0.956
A0A0J9X527	A0A0J9X6Z5	annotation not available	Belongs to the universal ribosomal protein uL16 family.	0.994
A0A0J9X527	A0A0J9X8D1	annotation not available	annotation not available	0.832
A0A0J9X527	A0A0J9X8U9	annotation not available	Belongs to the universal ribosomal protein uS2 family.	0.967
A0A0J9X527	A0A0J9X9Q2	annotation not available	Belongs to the universal ribosomal protein uS5 family.	0.967
A0A0J9X527	A0A0J9XAL2	annotation not available	annotation not available	0.994
A0A0J9X527	A0A0J9XAR9	annotation not available	annotation not available	0.981
A0A0J9X527	A0A0J9XEY0	annotation not available	annotation not available	0.980
A0A0J9X527	A0A0J9XIE1	annotation not available	annotation not available	0.996
A0A0J9X527	A0A0J9XLD6	annotation not available	annotation not available	0.991

page 1 of 6

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000105

Histidine biosynthetic process

5 of 13

2.3

3.87

1.46e-08

GO:0009073

Aromatic amino acid family biosynthetic process

4 of 17

2.08

2.57

5.44e-06

GO:0008652

Cellular amino acid biosynthetic process

9 of 183

1.4

2.25

3.71e-09

GO:0006520

Cellular amino acid metabolic process

10 of 311

1.22

1.76

3.71e-09

GO:0009095

Aromatic amino acid family biosynthetic process, prephenate pathway

2 of 2

2.71

1.56

0.0014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016836

Hydro-lyase activity

3 of 38

1.61

0.67

0.0478

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1823

0.45

0.33

0.0134

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1575

Aromatic amino acid family biosynthetic process, and Histidine biosynthesis

8 of 28

2.17

5.69

6.02e-14

CL:1515

Amino-acid biosynthesis, and Aminotransferase class IV

10 of 58

1.95

5.46

4.37e-16

CL:1608

Histidine biosynthesis

5 of 10

2.41

4.15

6.00e-09

CL:1611

Histidine biosynthesis

3 of 5

2.49

2.28

5.48e-05

CL:1576

Aromatic amino acid family biosynthetic process

3 of 16

1.98

1.56

0.00082

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

5 of 25

2.01

3.21

8.92e-08

map00340

Histidine metabolism

5 of 29

1.95

3.08

1.16e-07

map01230

Biosynthesis of amino acids

9 of 231

1.3

1.99

2.63e-09

map00401

Novobiocin biosynthesis

2 of 3

2.53

1.69

0.00076

map00360

Phenylalanine metabolism

3 of 36

1.63

1.37

0.00092

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

11 of 1419

0.6

0.52

8.49e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0368

Histidine biosynthesis

5 of 12

2.33

4.05

6.80e-09

KW-0028

Amino-acid biosynthesis

8 of 88

1.67

3.22

1.88e-10

KW-0057

Aromatic amino acid biosynthesis

3 of 14

2.04

1.79

0.00028

KW-0822

Tryptophan biosynthesis

2 of 6

2.23

1.26

0.0044

KW-0456

Lyase

4 of 110

1.27

0.99

0.0027

(more ...)

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