STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (330 aa)    
Predicted Functional Partners:
NTG1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
   
 0.902
A0A0J9XGF8
annotation not available
  
 0.861
A0A0J9XCF2
annotation not available
   
 
 0.819
A0A0J9X4U6
Belongs to the actin family.
 
 
    0.775
A0A0J9X4R5
Similar to Saccharomyces cerevisiae YKL114C APN1 Major apurinic/apyrimidinic endonuclease.
   
 
 0.745
A0A0J9X331
Similar to Yarrowia lipolytica YALI0E03124g [Yarrowia lipolytica CLIB 122].
   
 
 0.706
A0A0J9X4H9
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.706
A0A0J9X965
annotation not available
 
 
    0.704
A0A0J9XH25
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.699
A0A0J9X7T3
annotation not available
    
  0.696
Your Current Organism:
Geotrichum candidum
NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis
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