A0A0J9XD35 protein (Geotrichum candidum) - STRING interaction network

Nodes:

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

A0A0J9XD35

annotation not available (336 aa)

Predicted Functional Partners:

A0A0J9XB00

0.972

A0A0J9X2F1

0.953

A0A0J9XD24

0.941

A0A0J9XE02

0.941

A0A0J9XK51

0.935

A0A0J9XIW3

0.918

A0A0J9XHC8

0.907

A0A0J9X7A0

0.892

A0A0J9X2Y0

0.820

A0A0J9X3V3

0.800

Your Current Organism:

Geotrichum candidum

NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J9X2F1	A0A0J9X2Y0	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	annotation not available	0.978
A0A0J9X2F1	A0A0J9X3V3	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	Belongs to the GroES chaperonin family.	0.840
A0A0J9X2F1	A0A0J9X7A0	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	annotation not available	0.880
A0A0J9X2F1	A0A0J9XB00	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	Similar to Saccharomyces cerevisiae YOR027W STI1 Hsp90 cochaperone.	0.986
A0A0J9X2F1	A0A0J9XD24	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin).	0.931
A0A0J9X2F1	A0A0J9XD35	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	annotation not available	0.953
A0A0J9X2F1	A0A0J9XE02	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin).	0.931
A0A0J9X2F1	A0A0J9XHC8	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	annotation not available	0.895
A0A0J9X2Y0	A0A0J9X2F1	annotation not available	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	0.978
A0A0J9X2Y0	A0A0J9X7A0	annotation not available	annotation not available	0.486
A0A0J9X2Y0	A0A0J9XB00	annotation not available	Similar to Saccharomyces cerevisiae YOR027W STI1 Hsp90 cochaperone.	0.939
A0A0J9X2Y0	A0A0J9XD24	annotation not available	Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin).	0.917
A0A0J9X2Y0	A0A0J9XD35	annotation not available	annotation not available	0.820
A0A0J9X2Y0	A0A0J9XE02	annotation not available	Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin).	0.917
A0A0J9X2Y0	A0A0J9XHC8	annotation not available	annotation not available	0.892
A0A0J9X2Y0	A0A0J9XIW3	annotation not available	Uncharacterized protein.	0.926
A0A0J9X2Y0	A0A0J9XK51	annotation not available	Flavin_Reduct domain-containing protein.	0.958
A0A0J9X3V3	A0A0J9X2F1	Belongs to the GroES chaperonin family.	Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family.	0.840
A0A0J9X3V3	A0A0J9X7A0	Belongs to the GroES chaperonin family.	annotation not available	0.534
A0A0J9X3V3	A0A0J9XB00	Belongs to the GroES chaperonin family.	Similar to Saccharomyces cerevisiae YOR027W STI1 Hsp90 cochaperone.	0.505

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016192

Vesicle-mediated transport

10 of 352

1.5

2.83

1.74e-11

GO:0006888

Endoplasmic reticulum to Golgi vesicle-mediated transport

4 of 74

1.78

1.74

0.00017

GO:0048205

COPI coating of Golgi vesicle

2 of 2

3.04

1.6

0.0013

GO:0006887

Exocytosis

3 of 38

1.94

1.45

0.0013

GO:0046907

Intracellular transport

7 of 494

1.19

1.31

2.31e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005096

GTPase activator activity

7 of 122

1.8

3.21

6.20e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030126

COPI vesicle coat

2 of 9

2.39

0.81

0.0327

GO:0005794

Golgi apparatus

4 of 268

1.22

0.64

0.0327

GO:0031410

Cytoplasmic vesicle

4 of 278

1.2

0.63

0.0327

GO:0005737

Cytoplasm

10 of 4900

0.35

0.25

0.0461

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:17015

Haemolysin-III related, and ArfGAP domain superfamily

4 of 17

2.41

2.83

3.91e-06

CL:17019

ArfGAP domain superfamily

3 of 6

2.74

2.6

1.60e-05

CL:5042

COPI vesicle coat, and ADP-ribosylation factor 1-5

3 of 12

2.44

2.28

5.03e-05

CL:4742

Vesicle-mediated transport, and RAB geranylgeranylation

6 of 171

1.59

2.07

3.91e-06

CL:4747

Exocytosis, and RAB geranylgeranylation

3 of 41

1.91

1.47

0.0011

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04144

Endocytosis

10 of 230

1.68

3.98

1.18e-14

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6811434

COPI-dependent Golgi-to-ER retrograde traffic

4 of 65

1.83

1.69

0.00029

MAP-6807878

COPI-mediated anterograde transport

4 of 66

1.83

1.68

0.00029

MAP-8856688

Golgi-to-ER retrograde transport

4 of 80

1.74

1.63

0.00029

MAP-199977

ER to Golgi Anterograde Transport

4 of 118

1.57

1.38

0.00071

MAP-948021

Transport to the Golgi and subsequent modification

4 of 121

1.56

1.37

0.00071

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0863

Zinc-finger

7 of 466

1.22

1.41

9.42e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038508

ArfGAP domain superfamily

7 of 10

2.89

7.64

2.87e-15

IPR037278

ARFGAP/RecO-like zinc finger

7 of 10

2.89

7.64

2.87e-15

IPR001164

Arf GTPase activating protein

7 of 10

2.89

7.64

2.87e-15

IPR005225

Small GTP-binding protein domain

3 of 76

1.64

0.72

0.0364

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00105

Putative GTP-ase activating proteins for the small GTPase, ARF

7 of 10

2.89

8.12

3.13e-16

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