STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0J9XFZ3Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (929 aa)    
Predicted Functional Partners:
A0A0J9X3P7
Similar to Saccharomyces cerevisiae YJL026W RNR2 Ribonucleotide-diphosphate reductase (RNR).
  
 0.962
A0A0J9X9A2
Similar to Saccharomyces cerevisiae YGR180C RNR4 Ribonucleotide-diphosphate reductase (RNR).
  
 0.962
A0A0J9X659
annotation not available
  
 0.864
A0A0J9X802
Similar to Saccharomyces cerevisiae YCL035C GRX1 Glutathione-dependent disulfide oxidoreductase.
  
 0.864
A0A0J9XCN2
annotation not available
  
 0.864
A0A0J9X9U4
DNA helicase; Belongs to the MCM family.
   
 
 0.842
A0A0J9XGE2
annotation not available
  
  
 0.824
A0A0J9XBP2
DNA helicase; Belongs to the MCM family.
   
 
 0.814
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.805
A0A0J9X5Q5
DNA helicase; Belongs to the MCM family.
   
 
 0.798
Your Current Organism:
Geotrichum candidum
NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis
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