A0A0J9XG50 protein (Geotrichum candidum) - STRING interaction network

Nodes:

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A0A0J9XG50

annotation not available (423 aa)

Predicted Functional Partners:

A0A0J9XC40

0.917

A0A0J9XHN2

0.864

A0A0J9YHD8

0.864

A0A0J9X3X5

0.642

A0A0J9XCZ9

0.464

A0A0J9X5A7

0.432

Your Current Organism:

Geotrichum candidum

NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J9X3X5	A0A0J9XG50	annotation not available	annotation not available	0.642
A0A0J9X5A7	A0A0J9XG50	ER lumen protein-retaining receptor.	annotation not available	0.432
A0A0J9X5A7	A0A0J9XHN2	ER lumen protein-retaining receptor.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.426
A0A0J9X5A7	A0A0J9YHD8	ER lumen protein-retaining receptor.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.426
A0A0J9XC40	A0A0J9XCZ9	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	0.850
A0A0J9XC40	A0A0J9XG50	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	annotation not available	0.917
A0A0J9XC40	A0A0J9XHN2	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.964
A0A0J9XC40	A0A0J9YHD8	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.964
A0A0J9XCZ9	A0A0J9XC40	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	0.850
A0A0J9XCZ9	A0A0J9XG50	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	annotation not available	0.464
A0A0J9XCZ9	A0A0J9XHN2	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.881
A0A0J9XCZ9	A0A0J9YHD8	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.881
A0A0J9XG50	A0A0J9X3X5	annotation not available	annotation not available	0.642
A0A0J9XG50	A0A0J9X5A7	annotation not available	ER lumen protein-retaining receptor.	0.432
A0A0J9XG50	A0A0J9XC40	annotation not available	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	0.917
A0A0J9XG50	A0A0J9XCZ9	annotation not available	Similar to Saccharomyces cerevisiae YPL206C PGC1 Phosphatidyl Glycerol phospholipase C.	0.464
A0A0J9XG50	A0A0J9XHN2	annotation not available	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.864
A0A0J9XG50	A0A0J9YHD8	annotation not available	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	0.864
A0A0J9XHN2	A0A0J9X5A7	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	ER lumen protein-retaining receptor.	0.426
A0A0J9XHN2	A0A0J9XC40	Similar to Saccharomyces cerevisiae YPL110C GDE1 Glycerophosphocholine (GroPCho) phosphodiesterase.	Similar to Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor.	0.964

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031640

Killing of cells of another organism

4 of 10

2.34

2.66

7.38e-06

GO:1900191

Negative regulation of single-species biofilm formation

4 of 11

2.3

2.64

7.38e-06

GO:0042742

Defense response to bacterium

4 of 11

2.3

2.64

7.38e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0001716

L-amino-acid oxidase activity

4 of 11

2.3

2.69

5.81e-06

GO:0048038

Quinone binding

4 of 31

1.85

1.99

5.47e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005576

Extracellular region

4 of 78

1.45

1.19

0.0014

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5946

Mixed, incl. 3-keto-disaccharide hydrolase, and Gfo/Idh/MocA-like oxidoreductase, bacterial type, C-terminal

6 of 35

1.97

3.4

1.87e-08

CL:5745

Mixed, incl. Gfo/Idh/MocA-like oxidoreductase, N-terminal, and Xylose isomerase-like superfamily

10 of 172

1.5

2.9

6.49e-12

CL:5853

Haem-binding domain, putative, and Cell killing

3 of 21

1.89

1.33

0.0022

CL:5858

Putative membrane-bound dehydrogenase, and Senescence marker protein-30 (SMP-30)

2 of 6

2.26

1.09

0.0094

CL:5749

Mixed, incl. Six-bladed beta-propeller, TolB-like, and Xylose isomerase-like TIM barrel

4 of 86

1.41

1.07

0.0029

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0732

Signal

7 of 648

0.77

0.54

0.0083

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF06283

Trehalose utilisation

4 of 10

2.34

2.78

4.10e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR010496

3-keto-disaccharide hydrolase

5 of 19

2.16

3.08

5.00e-07

IPR029010

ThuA-like domain

4 of 10

2.34

2.74

5.10e-06

IPR029062

Class I glutamine amidotransferase-like

4 of 39

1.75

1.58

0.00041

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