A0A0J9XG90 protein (Geotrichum candidum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

A0A0J9XG90

annotation not available (996 aa)

Predicted Functional Partners:

A0A0J9X348

0.816

A0A0J9XAP8

0.816

A0A0J9XJ43

0.805

A0A0J9X5H3

0.793

A0A0J9XGK9

0.793

A0A0J9X4C2

0.741

A0A0J9XHY7

0.741

A0A0J9X717

0.740

A0A0J9X8X5

0.740

A0A0J9X6Q9

0.734

Your Current Organism:

Geotrichum candidum

NCBI taxonomy Id: 1173061
Other names: ATCC 22600 [[Endomyces geotrichum]], CBS 615.84 [[Galactomyces candidus]], CBS 772.71 [[Endomyces geotrichum]], Dipodascus geotrichum, Endomyces geotrichum, G. candidum, Galactomyces candidum, Galactomyces candidus, Galactomyces candidus de Hoog & M.T. Smith, 2004, Galactomyces geotrichum, Geotrichum sp. S9, JCM 6359 [[Endomyces geotrichum]], NRRL Y-17569 [[Endomyces geotrichum]], Oospora lactis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0J9X348	A0A0J9X4C2	Uncharacterized protein.	annotation not available	0.696
A0A0J9X348	A0A0J9XG90	Uncharacterized protein.	annotation not available	0.816
A0A0J9X348	A0A0J9XGK9	Uncharacterized protein.	Uncharacterized protein.	0.774
A0A0J9X348	A0A0J9XHY7	Uncharacterized protein.	annotation not available	0.696
A0A0J9X4C2	A0A0J9X348	annotation not available	Uncharacterized protein.	0.696
A0A0J9X4C2	A0A0J9X5H3	annotation not available	annotation not available	0.623
A0A0J9X4C2	A0A0J9X6Q9	annotation not available	annotation not available	0.817
A0A0J9X4C2	A0A0J9X717	annotation not available	annotation not available	0.403
A0A0J9X4C2	A0A0J9X8X5	annotation not available	annotation not available	0.403
A0A0J9X4C2	A0A0J9XAP8	annotation not available	Uncharacterized protein.	0.696
A0A0J9X4C2	A0A0J9XG90	annotation not available	annotation not available	0.741
A0A0J9X4C2	A0A0J9XGK9	annotation not available	Uncharacterized protein.	0.568
A0A0J9X5H3	A0A0J9X4C2	annotation not available	annotation not available	0.623
A0A0J9X5H3	A0A0J9XG90	annotation not available	annotation not available	0.793
A0A0J9X5H3	A0A0J9XGK9	annotation not available	Uncharacterized protein.	0.622
A0A0J9X5H3	A0A0J9XHY7	annotation not available	annotation not available	0.623
A0A0J9X6Q9	A0A0J9X4C2	annotation not available	annotation not available	0.817
A0A0J9X6Q9	A0A0J9XG90	annotation not available	annotation not available	0.734
A0A0J9X6Q9	A0A0J9XGK9	annotation not available	Uncharacterized protein.	0.999
A0A0J9X6Q9	A0A0J9XHY7	annotation not available	annotation not available	0.817

page 1 of 4

Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901607

Alpha-amino acid biosynthetic process

6 of 81

1.39

1.51

5.55e-05

GO:1901605

Alpha-amino acid metabolic process

7 of 139

1.22

1.29

5.55e-05

GO:0009084

Glutamine family amino acid biosynthetic process

3 of 23

1.63

1.07

0.0057

GO:0006082

Organic acid metabolic process

8 of 363

0.86

0.75

0.00036

GO:0006536

Glutamate metabolic process

2 of 9

1.87

0.75

0.0376

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2032

Cellular amino acid biosynthetic process, and Vitamin binding

7 of 117

1.3

1.52

1.08e-05

CL:2167

Valine, leucine and isoleucine biosynthesis, and Cysteine and methionine metabolism

4 of 47

1.45

1.09

0.0029

CL:1539

Mixed, incl. Pyruvate ferredoxin/flavodoxin oxidoreductase, and 3Fe-4S

2 of 6

2.04

0.8

0.0314

CL:1514

Mixed, incl. Citrate cycle (TCA cycle), and Aldehyde dehydrogenase domain

4 of 84

1.2

0.71

0.0189

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01230

Biosynthesis of amino acids

8 of 159

1.22

1.59

3.00e-07

map00250

Alanine, aspartate and glutamate metabolism

3 of 27

1.56

1.18

0.0025

map01110

Biosynthesis of secondary metabolites

9 of 440

0.83

0.8

1.65e-05

map01100

Metabolic pathways

11 of 1399

0.41

0.35

0.0012

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0028

Amino-acid biosynthesis

4 of 66

1.3

0.87

0.0083

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01558

Pyruvate ferredoxin/flavodoxin oxidoreductase

2 of 2

2.52

0.84

0.0296

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR019752

Pyruvate/ketoisovalerate oxidoreductase, catalytic domain

2 of 2

2.52

0.76

0.0410

IPR002880

Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain

2 of 2

2.52

0.76

0.0410

IPR002869

Pyruvate-flavodoxin oxidoreductase, central domain

2 of 2

2.52

0.76

0.0410

IPR029061

Thiamin diphosphate-binding fold

3 of 18

1.74

0.72

0.0410

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