STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABStage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (151 aa)    
Predicted Functional Partners:
SDK69389.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.998
SDK69301.1
RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.994
SDK88506.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 0.918
SDI97838.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
 0.900
SDK58619.1
Anti-sigma B factor antagonist.
  
 0.894
SDI09381.1
Stage II sporulation protein GA (sporulation sigma-E factor processing peptidase).
  
  
 0.883
SDL03579.1
Signal transduction histidine kinase.
  
 
 0.870
SDK88621.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
  
 0.864
SDI09288.1
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.861
SDH98887.1
PAS domain S-box-containing protein.
  
 
 0.855
Your Current Organism:
Paenibacillus typhae
NCBI taxonomy Id: 1174501
Other names: CGMCC 1.11012, DSM 25190, P. typhae, Paenibacillus sp. enrichment culture clone xj7, Paenibacillus sp. xj7, Paenibacillus typhae Kong et al. 2013, strain xj7
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