| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GWL_02060 | mnmA | GWL_02060 | GWL_02040 | NAD(P) transhydrogenase alpha subunit. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.554 |
| GWL_02060 | nadE | GWL_02060 | GWL_13340 | NAD(P) transhydrogenase alpha subunit. | Glutamine-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.880 |
| GWL_02060 | nadE-2 | GWL_02060 | GWL_39350 | NAD(P) transhydrogenase alpha subunit. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.880 |
| GWL_02060 | nudJ | GWL_02060 | GWL_02050 | NAD(P) transhydrogenase alpha subunit. | NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.759 |
| GWL_09940 | GWL_37360 | GWL_09940 | GWL_37360 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.447 |
| GWL_09940 | GWL_45400 | GWL_09940 | GWL_45400 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.542 |
| GWL_09940 | nadE | GWL_09940 | GWL_13340 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glutamine-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.806 |
| GWL_09940 | nadE-2 | GWL_09940 | GWL_39350 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.806 |
| GWL_09940 | nudJ | GWL_09940 | GWL_02050 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.730 |
| GWL_26850 | nudJ | GWL_26850 | GWL_02050 | Transmembrane Tfp pilus assembly FimV protein. | NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.776 |
| GWL_37360 | GWL_09940 | GWL_37360 | GWL_09940 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.447 |
| GWL_37360 | GWL_45400 | GWL_37360 | GWL_45400 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.536 |
| GWL_37360 | mnmA | GWL_37360 | GWL_02040 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.500 |
| GWL_37360 | nudJ | GWL_37360 | GWL_02050 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.766 |
| GWL_44510 | GWL_45400 | GWL_44510 | GWL_45400 | Adenylate cyclase. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.884 |
| GWL_44510 | nudJ | GWL_44510 | GWL_02050 | Adenylate cyclase. | NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.725 |
| GWL_44510 | ribB | GWL_44510 | GWL_29410 | Adenylate cyclase. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.891 |
| GWL_45400 | GWL_09940 | GWL_45400 | GWL_09940 | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.542 |
| GWL_45400 | GWL_37360 | GWL_45400 | GWL_37360 | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.536 |
| GWL_45400 | GWL_44510 | GWL_45400 | GWL_44510 | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate cyclase. | 0.884 |