Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GWL_05430NADP-dependent malic enzyme oxidoreductase. (758 aa)    
Predicted Functional Partners:
GWL_08760
2-oxoglutarate dehydrogenase E3 component lipoamide dehydrogenase.
  
 
 0.977
GWL_17820
Dihydrolipoamide dehydrogenase.
  
 
 0.977
GWL_23700
Malate synthase; Belongs to the malate synthase family.
  
 
 0.973
GWL_09940
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.964
GWL_01800
Pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 0.962
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.959
GWL_27720
NADP-dependent malic enzyme oxidoreductase.
  
 
 0.949
GWL_15420
Isocitrate lyase.
   
 
 0.947
GWL_20160
Indolepyruvate ferredoxin oxidoreductase subunit alpha/beta.
    
 0.945
GWL_36620
Indolepyruvate ferredoxin oxidoreductase subunit alpha/beta.
    
 0.945
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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