Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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cobDCobalamin biosynthesis transmembrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.941
GWL_21040
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.940
GWL_21020
Cobalamin biosynthesis protein.
 
  
 0.927
GWL_21070
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.926
GWL_32010
Hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family.
 
  
 0.906
cobD-2
Cobalamin biosynthesis CobD/CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
  
 
0.901
GWL_21090
Precorrin-3 methyltransferase/precorrin-6x reductase oxidoreductase.
 
 
 0.836
GWL_21140
precorrin-8X methylmutase.
 
 
 0.815
GWL_21060
Cobyrinic acid A,c-diamide synthase.
 
 
 0.733
GWL_15930
Transmembrane protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.717
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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