| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GWL_15170 | GWL_24750 | GWL_15170 | GWL_24750 | Aspartate aminotransferase. | Glutamine synthetase. | 0.539 |
| GWL_15170 | GWL_32340 | GWL_15170 | GWL_32340 | Aspartate aminotransferase. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.886 |
| GWL_15170 | GWL_33020 | GWL_15170 | GWL_33020 | Aspartate aminotransferase. | Glutamate synthase small subunit oxidoreductase. | 0.677 |
| GWL_15170 | GWL_33030 | GWL_15170 | GWL_33030 | Aspartate aminotransferase. | Glutamate synthase large subunit oxidoreductase. | 0.941 |
| GWL_15170 | GWL_33110 | GWL_15170 | GWL_33110 | Aspartate aminotransferase. | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D protein; Belongs to the asparaginase 1 family. | 0.662 |
| GWL_15170 | GWL_43670 | GWL_15170 | GWL_43670 | Aspartate aminotransferase. | Proline dehydrogenase/proline oxidase delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.764 |
| GWL_15170 | murI | GWL_15170 | GWL_09930 | Aspartate aminotransferase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.887 |
| GWL_15620 | GWL_24750 | GWL_15620 | GWL_24750 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine synthetase. | 0.695 |
| GWL_15620 | GWL_32340 | GWL_15620 | GWL_32340 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.459 |
| GWL_15620 | GWL_33030 | GWL_15620 | GWL_33030 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate synthase large subunit oxidoreductase. | 0.540 |
| GWL_15620 | murD | GWL_15620 | GWL_44790 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.608 |
| GWL_15620 | murI | GWL_15620 | GWL_09930 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.912 |
| GWL_15620 | purL | GWL_15620 | GWL_16530 | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.731 |
| GWL_24750 | GWL_15170 | GWL_24750 | GWL_15170 | Glutamine synthetase. | Aspartate aminotransferase. | 0.539 |
| GWL_24750 | GWL_15620 | GWL_24750 | GWL_15620 | Glutamine synthetase. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.695 |
| GWL_24750 | GWL_32340 | GWL_24750 | GWL_32340 | Glutamine synthetase. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.884 |
| GWL_24750 | GWL_33020 | GWL_24750 | GWL_33020 | Glutamine synthetase. | Glutamate synthase small subunit oxidoreductase. | 0.932 |
| GWL_24750 | GWL_33030 | GWL_24750 | GWL_33030 | Glutamine synthetase. | Glutamate synthase large subunit oxidoreductase. | 0.965 |
| GWL_24750 | GWL_33110 | GWL_24750 | GWL_33110 | Glutamine synthetase. | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D protein; Belongs to the asparaginase 1 family. | 0.811 |
| GWL_24750 | GWL_43670 | GWL_24750 | GWL_43670 | Glutamine synthetase. | Proline dehydrogenase/proline oxidase delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.926 |