Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lolAOuter-membrane lipoprotein-sorting protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (237 aa)    
Predicted Functional Partners:
GWL_22000
Lipoprotein release ABC transporter permease.
 
 
 
 0.927
GWL_32960
Outer-membrane lipoprotein lolB precursor lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
 
 
 0.908
lolD
Lipoprotein release ABC transporter ATPase; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
   
 
 0.798
GWL_25150
Antimicrobial peptide ABC transporter ATPase.
   
 
 0.795
lptD
Organic solvent tolerance transmembrane protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
   
 0.758
GWL_13440
DNA translocase FtsK2 transmembrane protein.
  
  
 0.750
macB
Antimicrobial peptide ABC transporter ATPase; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.748
GWL_00990
DNA polymerase III subunit delta.
 
     0.717
bamE
Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 
 0.701
GWL_02480
N-acetylmuramoyl-l-alanine amidase.
    
 
 0.699
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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