def protein (Herbaspirillum sp. GW103) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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def

N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (178 aa)

Predicted Functional Partners:

rplU

0.848

GWL_14080

0.831

tig

0.830

rplD

0.808

rplM

0.804

rpsT

0.802

rplI

0.801

rplV

0.798

fmt

0.796

rplC

0.794

Your Current Organism:

Herbaspirillum sp. GW103

NCBI taxonomy Id: 1175306
Other names: H. sp. GW103

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GWL_14080	def	GWL_14080	GWL_15960	50S ribosomal protein L20.	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.831
GWL_14080	rplC	GWL_14080	GWL_42920	50S ribosomal protein L20.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.994
GWL_14080	rplD	GWL_14080	GWL_42930	50S ribosomal protein L20.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.991
GWL_14080	rplI	GWL_14080	GWL_15030	50S ribosomal protein L20.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.994
GWL_14080	rplM	GWL_14080	GWL_32240	50S ribosomal protein L20.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.997
GWL_14080	rplU	GWL_14080	GWL_45220	50S ribosomal protein L20.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.994
GWL_14080	rplV	GWL_14080	GWL_42970	50S ribosomal protein L20.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.993
GWL_14080	rpsT	GWL_14080	GWL_08000	50S ribosomal protein L20.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.968
GWL_14080	tig	GWL_14080	GWL_20520	50S ribosomal protein L20.	Peptidyl-prolyl cis/trans isomerase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.972
def	GWL_14080	GWL_15960	GWL_14080	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L20.	0.831
def	fmt	GWL_15960	GWL_37380	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.796
def	rplC	GWL_15960	GWL_42920	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.794
def	rplD	GWL_15960	GWL_42930	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.808
def	rplI	GWL_15960	GWL_15030	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.801
def	rplM	GWL_15960	GWL_32240	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.804
def	rplU	GWL_15960	GWL_45220	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.848
def	rplV	GWL_15960	GWL_42970	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.798
def	rpsT	GWL_15960	GWL_08000	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.802
def	tig	GWL_15960	GWL_20520	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Peptidyl-prolyl cis/trans isomerase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.830
fmt	def	GWL_37380	GWL_15960	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	N-formylmethionyl-tRNA deformylase/polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.796

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