| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GWL_02110 | GWL_12210 | GWL_02110 | GWL_12210 | 2-octaprenyl-6-methoxyphenol hydroxylase. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.445 |
| GWL_02110 | GWL_45210 | GWL_02110 | GWL_45210 | 2-octaprenyl-6-methoxyphenol hydroxylase. | Octaprenyldiphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.766 |
| GWL_02110 | tpm | GWL_02110 | GWL_31720 | 2-octaprenyl-6-methoxyphenol hydroxylase. | Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. | 0.818 |
| GWL_02110 | ubiA | GWL_02110 | GWL_31710 | 2-octaprenyl-6-methoxyphenol hydroxylase. | 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.810 |
| GWL_02110 | ubiD | GWL_02110 | GWL_29360 | 2-octaprenyl-6-methoxyphenol hydroxylase. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.774 |
| GWL_02110 | ubiG | GWL_02110 | GWL_30630 | 2-octaprenyl-6-methoxyphenol hydroxylase. | 3-demethylubiquinone-9 3-methyl transferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.992 |
| GWL_02110 | ubiX | GWL_02110 | GWL_33570 | 2-octaprenyl-6-methoxyphenol hydroxylase. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.723 |
| GWL_12210 | GWL_02110 | GWL_12210 | GWL_02110 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.445 |
| GWL_12210 | GWL_36120 | GWL_12210 | GWL_36120 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.582 |
| GWL_12210 | GWL_45210 | GWL_12210 | GWL_45210 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Octaprenyldiphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.763 |
| GWL_12210 | tpm | GWL_12210 | GWL_31720 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. | 0.431 |
| GWL_12210 | ubiA | GWL_12210 | GWL_31710 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.844 |
| GWL_12210 | ubiG | GWL_12210 | GWL_30630 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-methyl transferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.601 |
| GWL_33920 | ubiA | GWL_33920 | GWL_31710 | 4-hydroxybenzoyl-CoA thioesterase. | 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.819 |
| GWL_33920 | ubiC | GWL_33920 | GWL_45550 | 4-hydroxybenzoyl-CoA thioesterase. | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.824 |
| GWL_36120 | GWL_12210 | GWL_36120 | GWL_12210 | 2-polyprenyl-6-methoxyphenol hydroxylase. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.582 |
| GWL_36120 | GWL_45210 | GWL_36120 | GWL_45210 | 2-polyprenyl-6-methoxyphenol hydroxylase. | Octaprenyldiphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.764 |
| GWL_36120 | tpm | GWL_36120 | GWL_31720 | 2-polyprenyl-6-methoxyphenol hydroxylase. | Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. | 0.794 |
| GWL_36120 | ubiA | GWL_36120 | GWL_31710 | 2-polyprenyl-6-methoxyphenol hydroxylase. | 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.813 |
| GWL_36120 | ubiD | GWL_36120 | GWL_29360 | 2-polyprenyl-6-methoxyphenol hydroxylase. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.892 |