Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
hprKHpr kinase and phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (312 aa)    
Predicted Functional Partners:
GWL_32900
'nitrogen regulatory IIA (Enzyme IIA-NTR) (Phosphotransferase enzyme II, A component) transcription regulator'.
 
   
 0.925
GWL_42700
Phosphocarrier protein HPr.
 
 
 
 0.875
GWL_42710
Phosphoenolpyruvate-protein phosphotransferase transmembrane protein; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.859
GWL_32920
P-loop-containing kinase; Displays ATPase and GTPase activities.
 
   
 0.703
GWL_42690
PTS system mannose/fructose-specific transporter subunit IIA.
 
   
 0.668
lgt
Prolipoprotein diacylglyceryl transferase transmembrane protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.636
GWL_33550
Ribosome hibernation protein YhbH.
 
   
 0.549
GWL_24340
Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
     0.491
GWL_42250
Ferrous iron transport B transmembrane protein.
  
    0.460
GWL_33030
Glutamate synthase large subunit oxidoreductase.
  
  
 0.414
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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