Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
GWL_38610Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (594 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase oxidoreductase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.917
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.895
GWL_11690
Acetolactate synthase isozyme III small regulatory subunit.
 
 
 0.860
GWL_09760
Para-aminobenzoate synthetase component I protein.
  
 0.848
GWL_41560
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 0.819
GWL_38620
Metal-dependent hydrolase.
 
     0.818
glk
Glucokinase; Belongs to the bacterial glucokinase family.
  
 
 0.811
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.796
GWL_11680
Acetolactate synthase isozyme III large subunit.
 
 0.781
GWL_38600
Short-chain dehydrogenase.
 
     0.779
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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