| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GWL_09940 | GWL_37360 | GWL_09940 | GWL_37360 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.447 |
| GWL_09940 | GWL_39340 | GWL_09940 | GWL_39340 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NMN adenylyltransferase/nudix hydrolase. | 0.730 |
| GWL_09940 | GWL_39380 | GWL_09940 | GWL_39380 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NTP pyrophosphohydrolase. | 0.730 |
| GWL_09940 | GWL_45400 | GWL_09940 | GWL_45400 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.542 |
| GWL_09940 | nadE | GWL_09940 | GWL_13340 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glutamine-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.806 |
| GWL_09940 | nadE-2 | GWL_09940 | GWL_39350 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.806 |
| GWL_37360 | GWL_09940 | GWL_37360 | GWL_09940 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.447 |
| GWL_37360 | GWL_39340 | GWL_37360 | GWL_39340 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NMN adenylyltransferase/nudix hydrolase. | 0.819 |
| GWL_37360 | GWL_39380 | GWL_37360 | GWL_39380 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NTP pyrophosphohydrolase. | 0.766 |
| GWL_37360 | GWL_45400 | GWL_37360 | GWL_45400 | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.536 |
| GWL_39340 | GWL_09940 | GWL_39340 | GWL_09940 | NMN adenylyltransferase/nudix hydrolase. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.730 |
| GWL_39340 | GWL_37360 | GWL_39340 | GWL_37360 | NMN adenylyltransferase/nudix hydrolase. | Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.819 |
| GWL_39340 | GWL_39370 | GWL_39340 | GWL_39370 | NMN adenylyltransferase/nudix hydrolase. | Cysteine hydrolases superfamily protein. | 0.674 |
| GWL_39340 | GWL_39380 | GWL_39340 | GWL_39380 | NMN adenylyltransferase/nudix hydrolase. | NTP pyrophosphohydrolase. | 0.789 |
| GWL_39340 | GWL_44510 | GWL_39340 | GWL_44510 | NMN adenylyltransferase/nudix hydrolase. | Adenylate cyclase. | 0.767 |
| GWL_39340 | GWL_45400 | GWL_39340 | GWL_45400 | NMN adenylyltransferase/nudix hydrolase. | Ribonucleoside reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.772 |
| GWL_39340 | nadE | GWL_39340 | GWL_13340 | NMN adenylyltransferase/nudix hydrolase. | Glutamine-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.954 |
| GWL_39340 | nadE-2 | GWL_39340 | GWL_39350 | NMN adenylyltransferase/nudix hydrolase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.984 |
| GWL_39340 | pncB-2 | GWL_39340 | GWL_39360 | NMN adenylyltransferase/nudix hydrolase. | Nicotinic acid phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.961 |
| GWL_39340 | ribB | GWL_39340 | GWL_29410 | NMN adenylyltransferase/nudix hydrolase. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.731 |