Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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GWL_42710Phosphoenolpyruvate-protein phosphotransferase transmembrane protein; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (596 aa)    
Predicted Functional Partners:
GWL_42700
Phosphocarrier protein HPr.
 
 0.999
GWL_32900
'nitrogen regulatory IIA (Enzyme IIA-NTR) (Phosphotransferase enzyme II, A component) transcription regulator'.
 
 
 0.939
hprK
Hpr kinase and phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.859
GWL_42690
PTS system mannose/fructose-specific transporter subunit IIA.
 
   
 0.858
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.816
GWL_01810
Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.757
GWL_20160
Indolepyruvate ferredoxin oxidoreductase subunit alpha/beta.
     
 0.744
GWL_36620
Indolepyruvate ferredoxin oxidoreductase subunit alpha/beta.
     
 0.744
GWL_32840
Oxidoreductase.
    
 0.720
GWL_05430
NADP-dependent malic enzyme oxidoreductase.
  
 
 0.681
Your Current Organism:
Herbaspirillum sp. GW103
NCBI taxonomy Id: 1175306
Other names: H. sp. GW103
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