STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJF07696.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (208 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
EJF06268.1
PFAM: Delta-aminolevulinic acid dehydratase; IMG reference gene:2508610948_SP; Belongs to the ALAD family.
  
 0.943
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.909
EJF06126.1
ABC-type transport system involved in cytochrome c biogenesis, permease component; PFAM: ResB-like family; Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB.
  
    0.872
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 0.807
EJF06276.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
  
    0.774
EJF07006.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
  
    0.708
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.
  
 
 0.669
EJF07695.1
Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.604
EJF07697.1
PFAM: McrBC 5-methylcytosine restriction system component.
       0.565
Your Current Organism:
Thiovulum sp. ES
NCBI taxonomy Id: 1177931
Other names: T. sp. ES
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