STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF08617.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (321 aa)    
Predicted Functional Partners:
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.994
SFE76770.1
Thiamine-phosphate diphosphorylase.
 
 
 0.993
SFE76838.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
  
  
 
0.969
SFE76801.1
Sulfur carrier protein ThiS.
  
 
  0.875
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.833
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
     
 0.816
SFF08596.1
1-acyl-sn-glycerol-3-phosphate acyltransferases.
       0.781
SFE58661.1
Molybdopterin or thiamine biosynthesis adenylyltransferase.
 
  
 0.706
SFF08629.1
Rubredoxin.
  
    0.652
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
    
 0.576
Your Current Organism:
Acidovorax wautersii
NCBI taxonomy Id: 1177982
Other names: A. wautersii, Acidovorax sp. NF1078, Acidovorax sp. NF1598, Acidovorax sp. NF1715, Acidovorax wautersii Vaneechoutte et al. 2013, CCUG 62584, DSM 27981, LMG 26971, LMG:26971
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.