SHI69204.1 protein (Arenitalea lutea) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

SHI69204.1

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB. (409 aa)

Predicted Functional Partners:

SHI40182.1

0.894

SHI69251.1

0.888

SHI69234.1

0.839

SHI38565.1

0.663

SHJ09199.1

0.614

SHI69314.1

0.603

SHI87709.1

0.596

SHI84745.1

0.594

SHI35518.1

0.570

SHI74688.1

0.554

Your Current Organism:

Arenitalea lutea

NCBI taxonomy Id: 1178825
Other names: A. lutea, Arenitalea lutea Zhang et al. 2013, CGMCC 1.12213, Flavobacteriaceae bacterium P7-3-5, KACC 16457, strain P7-3-5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHI35518.1	SHI69204.1	SAMN05216261_0411	SAMN05216261_1404	Hypothetical protein.	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	0.570
SHI35518.1	SHI69251.1	SAMN05216261_0411	SAMN05216261_1406	Hypothetical protein.	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain.	0.407
SHI38565.1	SHI69204.1	SAMN05216261_0555	SAMN05216261_1404	PAS domain S-box-containing protein.	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	0.663
SHI38565.1	SHI74688.1	SAMN05216261_0555	SAMN05216261_1657	PAS domain S-box-containing protein.	Tetratricopeptide repeat-containing protein.	0.568
SHI38565.1	SHI84745.1	SAMN05216261_0555	SAMN05216261_1972	PAS domain S-box-containing protein.	Flp pilus assembly protein TadD, contains TPR repeats.	0.729
SHI38565.1	SHJ09199.1	SAMN05216261_0555	SAMN05216261_2760	PAS domain S-box-containing protein.	Tetratricopeptide repeat-containing protein.	0.770
SHI40182.1	SHI69204.1	SAMN05216261_0631	SAMN05216261_1404	Cell division protein FtsX; Required for cell division and gliding motility. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	0.894
SHI69204.1	SHI35518.1	SAMN05216261_1404	SAMN05216261_0411	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Hypothetical protein.	0.570
SHI69204.1	SHI38565.1	SAMN05216261_1404	SAMN05216261_0555	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	PAS domain S-box-containing protein.	0.663
SHI69204.1	SHI40182.1	SAMN05216261_1404	SAMN05216261_0631	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Cell division protein FtsX; Required for cell division and gliding motility. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	0.894
SHI69204.1	SHI69234.1	SAMN05216261_1404	SAMN05216261_1405	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Protein of unknown function.	0.839
SHI69204.1	SHI69251.1	SAMN05216261_1404	SAMN05216261_1406	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain.	0.888
SHI69204.1	SHI69314.1	SAMN05216261_1404	SAMN05216261_1409	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Glucose-1-phosphate thymidylyltransferase; Manually curated.	0.603
SHI69204.1	SHI74688.1	SAMN05216261_1404	SAMN05216261_1657	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Tetratricopeptide repeat-containing protein.	0.554
SHI69204.1	SHI84745.1	SAMN05216261_1404	SAMN05216261_1972	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Flp pilus assembly protein TadD, contains TPR repeats.	0.594
SHI69204.1	SHI87709.1	SAMN05216261_1404	SAMN05216261_2103	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Gliding motility-associated C-terminal domain-containing protein.	0.596
SHI69204.1	SHJ09199.1	SAMN05216261_1404	SAMN05216261_2760	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	Tetratricopeptide repeat-containing protein.	0.614
SHI69234.1	SHI69204.1	SAMN05216261_1405	SAMN05216261_1404	Protein of unknown function.	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.	0.839
SHI69234.1	SHI69251.1	SAMN05216261_1405	SAMN05216261_1406	Protein of unknown function.	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain.	0.785
SHI69234.1	SHI69314.1	SAMN05216261_1405	SAMN05216261_1409	Protein of unknown function.	Glucose-1-phosphate thymidylyltransferase; Manually curated.	0.603

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.676

expected number of edges:

16

PPI enrichment p-value:

0.0223

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006366

Transcription by RNA polymerase II

6 of 179

1.86

2.89

1.81e-07

GO:0006351

Transcription, DNA-templated

7 of 313

1.69

2.59

1.81e-07

GO:0006367

Transcription initiation from RNA polymerase II promoter

3 of 33

2.3

1.83

0.00034

GO:0045948

Positive regulation of translational initiation

2 of 19

2.36

1.0

0.0148

GO:0030150

Protein import into mitochondrial matrix

2 of 23

2.28

0.92

0.0199

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

4 of 21

2.62

3.24

8.12e-07

GO:0031369

Translation initiation factor binding

2 of 17

2.41

1.0

0.0146

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005665

RNA polymerase II, core complex

5 of 14

2.89

5.66

2.56e-11

GO:0055029

Nuclear DNA-directed RNA polymerase complex

7 of 97

2.2

5.0

9.66e-12

GO:0016591

RNA polymerase II, holoenzyme

6 of 71

2.27

4.73

1.04e-10

GO:0005744

TIM23 mitochondrial import inner membrane translocase complex

2 of 9

2.69

1.65

0.00095

GO:0005654

Nucleoplasm

7 of 2180

0.85

0.7

0.0010

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9495

RNA polymerase II, core complex

5 of 8

3.13

5.64

4.38e-11

CL:9468

RNA Polymerase II Pre-transcription Events, and RNA Polymerase III Transcription Initiation From Type 1 Promoter

7 of 181

1.93

3.78

6.36e-10

CL:9476

RNA Polymerase II Pre-transcription Events, and Transcription elongation factor complex

6 of 126

2.02

3.59

8.63e-09

CL:32588

Mitochondrial protein import, and Protein insertion into mitochondrial inner membrane

3 of 38

2.24

1.82

0.00034

CL:32638

TIM23 mitochondrial import inner membrane translocase complex

2 of 5

2.94

1.54

0.0016

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

6 of 54

2.38

5.25

1.69e-11

map04623

Cytosolic DNA-sensing pathway

2 of 68

1.81

0.71

0.0443

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6803529

FGFR2 alternative splicing

6 of 27

2.69

5.95

3.21e-12

MAP-77075

RNA Pol II CTD phosphorylation and interaction with CE

6 of 32

2.61

5.83

4.00e-12

MAP-72086

mRNA Capping

6 of 33

2.6

5.81

4.00e-12

MAP-113418

Formation of the Early Elongation Complex

6 of 36

2.56

5.77

4.00e-12

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

6 of 52

2.4

5.21

2.34e-11

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

7 of 94

2.21

5.03

9.54e-12

GOCC:0055029

Nuclear DNA-directed RNA polymerase complex

6 of 81

2.21

4.39

4.47e-10

GOCC:0005665

RNA polymerase II, core complex

3 of 8

2.91

2.97

3.65e-06

GOCC:0016591

RNA polymerase II, holoenzyme

4 of 59

2.17

2.71

3.65e-06

GOCC:0005744

TIM23 mitochondrial import inner membrane translocase complex

2 of 9

2.69

1.55

0.0015

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

6 of 30

2.64

6.1

1.23e-12

KW-0804

Transcription

7 of 517

1.47

2.18

1.26e-07

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00662

RNA polymerases D

2 of 2

3.34

1.69

0.00092

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