STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALS36064.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)    
Predicted Functional Partners:
ALS36063.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.817
ALS36996.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.778
ALS36061.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
ALS36062.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
tdk
Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.720
ALS36065.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.707
ALS35769.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.657
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.656
ALS35629.1
Deoxyadenosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.600
ALS38253.1
Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.599
Your Current Organism:
Enterococcus rotai
NCBI taxonomy Id: 118060
Other names: CCM 4630, CCUG 61593, E. rotai, Enterococcus rotai Sedlacek et al. 2013, Enterococcus sp. CCM 4360, LMG 26678, LMG:26678
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.