STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
korB2-oxoglutarate synthase subunit KorB; sp|O27113|KORB_METTH;evalue=8e-118; PctID=68.88; score=423. (288 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate synthase subunit KorA; sp|O27112|KORA_METTH;evalue=3e-152; PctID=70.81; score=538.
 0.999
korC
2-oxoglutarate synthase subunit KorC; sp|P80906|KORC_METTM;evalue=2e-071; PctID=71.04; score=268.
 0.999
porA
Pyruvate synthase subunit PorA; sp|P56810|PORA_METTH;evalue=2e-147; PctID=66.49; score=522.
 
 0.994
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.989
porC
Pyruvate synthase subunit PorC; sp|O27772|PORC_METTH;evalue=3e-065; PctID=69.49; score=247.
  
 0.986
porD
Pyruvate synthase subunit PorD; sp|P80903|PORD_METTM;evalue=4e-038; PctID=82.50; score=156.
  
 0.986
vorB
Ketoisovalerate oxidoreductase subunit VorB; sp|O26800|VORB_METTH;evalue=1e-155; PctID=76.86; score=549.
 
 0.983
MCBB_0233
Putative ferredoxin MJ0146; sp|Q57610|FER3_METJA;evalue=4e-017; PctID=56.45; score=86.7.
 
 
 0.978
MCBB_0936
Acetate-CoA ligase [ADP-forming] I; Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate. Can use other substrates such as propionyl-CoA and butyryl-CoA, but not phenylacetyl-CoA. Seems to be involved primarily in the conversion of acetyl-CoA to acetate. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. acetyl-CoA. Kinetic parameters: KM=10 uM for acetyl-CoA; KM=7 uM for ADP; KM=110 uM for phosphate; KM=340 uM for acetate; KM=100 uM for phenylacetate; KM=133 uM for ATP; KM=27 uM for CoA; Note=kc [...]
    
 0.954
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.943
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.