STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_0342Putative protein MTH_886; sp|O26972|Y886_METTH;evalue=3e-020; PctID=59.21; score=97.1. (91 aa)    
Predicted Functional Partners:
truB
Putative tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 0.996
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.991
MCBB_2063
Putative NOP5 family protein MJ0694; sp|Q58105|Y694_METJA;evalue=6e-049; PctID=38.70; score=195.
  
 
 0.952
tfb
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
  
 0.864
MCBB_1382
Putative protein VNG_1688C; sp|Q06847|Y1688_HALSA;evalue=3e-014; PctID=35.90; score=79.3.
   
   0.835
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.816
cshA
{ECO:0000255|HAMAP-Rule:MF_01493}; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'-and 3'-directions,has RNA-dependent ATPase activity. subfamily; sp|Q73EU1|CSHA_BACC1;evalue=2e-126; PctID=53.65; score=453; Belongs to the DEAD box helicase family.
  
 
 0.815
guaAB
GMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP.
  
  
 0.765
rps4
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.716
NOG1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. superfamily. OBG GTPase family. NOG subfamily. domain; sp|Q74ZK6|NOG1_ASHGO;evalue=1e-045; PctID=33.22; score=183.
  
 
 0.630
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
Server load: low (16%) [HD]