STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (287 aa)    
Predicted Functional Partners:
rpl13/rps9
Fused L13/S9 ribosomal protein; L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity). the 30S ribosomal subunit (By similarity). protein L13P family. protein S9P family. ribosomal subunit, and that they are not known to contact each other in the ribosome, this may be incorrectly predicted and should perhaps be two separate genes; sp|O26146|RLSX_METTH;evalue=9e-049; PctID=71.43; score=191.
  
  
 0.999
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
  
 0.999
GR
Maintains high levels of reduced glutathione in the chloroplast. disulfide + NADPH. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; Note=Binds 1 FAD per subunit; Mitochondrion Note=The majority of the protein is found in chloroplast, with only 3% in mitochondria. oxidoreductase family. Sequence=CAA42921.1; Type=Erroneous initiation; Evidence=; sp|P27456|GSHRP_PEA;evalue=6e-028; PctID=26.09; score=125.
 
 0.981
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.951
MCBB_0186
Phosphoglucomutase/phosphomannomutase{03|}; Catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate, and the interconversion of mannose 1-phosphate and mannose 6-phosphate. Also displays low activity with deoxyribose 1-phosphate and glucosamine 1-phosphate. 6-phosphate. phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Note=Can also use Ni(2+), Mn(2+) and Zn(2+), to a lesser extent; Kinetic parameters: KM=3.0 mM for glucose 1-phosphate; KM=3.2 mM for mannose 1-phosphate; KM=3.5 mM for 2-deoxyribose 1-phosphate; Vmax=690 umol/min/mg enzyme with glucose 1-ph [...]
 
 0.947
MCBB_0481
Putative sugar kinase MTH_1544; sp|O27587|Y1544_METTH;evalue=9e-009; PctID=34.91; score=61.2.
  
 0.936
MCBB_1015
Putative sugar kinase AF_0356; sp|O29891|Y356_ARCFU;evalue=9e-028; PctID=48.23; score=124; Belongs to the carbohydrate kinase PfkB family.
  
 0.936
glmM-2
Putative phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. glucosamine 6-phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Note=Binds 1 Mg(2+) ion per subunit; Rule:MF_01554}. Sequence=AAM06397.1; Type=Erroneous initiation; Evidence=; sp|Q8TLL2|GLMM_METAC;evalue=8e-050; PctID=30.16; score=198; {ECO:0000255|HAMAP-Rule:MF_01554}.
  
 0.936
purF
Amidophosphoribosyltransferase{ECO:0000255|HAMA P-Rule:MF_01931}; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.933
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.905
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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