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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
nit2Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. dicarboxylate + NH(3). NIT1/NIT2 family. ProRule:PRU00054}; sp|Q4VBV9|NIT2_DANRE;evalue=6e-081; PctID=52.04; score=300. (282 aa)    
Predicted Functional Partners:
MCBB_1468
Putative aspartate aminotransferase; sp|Q60317|AAT_METJA;evalue=8e-093; PctID=47.59; score=340.
 
 
 0.933
aspC
Aspartate aminotransferase; sp|O58489|AAT_PYRHO;evalue=7e-023; PctID=24.69; score=108.
  
  
  0.911
mdh-2
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate; sp|O26290|MDH_METTH;evalue=4e-108; PctID=59.01; score=391; {ECO:0000255|HAMAP-Rule:MF_00487}; Belongs to the LDH/MDH superfamily.
  
 0.863
korC
2-oxoglutarate synthase subunit KorC; sp|P80906|KORC_METTM;evalue=2e-071; PctID=71.04; score=268.
 
  
 0.840
pycA
Pyruvate carboxylase catalyzes a 2-step reaction,involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. oxaloacetate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Name=Co(2+); Xref=ChEBI:CHEBI:48828; pH dependence: Optimum pH is 8; Temperature dependence: Optimum temperature is 60 degrees Celsius.; ProRule:PRU00409}; sp|O27939|PYCA_METTH;evalue=0.0; PctID=76.54; score=767.
    
 0.833
korB
2-oxoglutarate synthase subunit KorB; sp|O27113|KORB_METTH;evalue=8e-118; PctID=68.88; score=423.
  
 
 0.817
korA
2-oxoglutarate synthase subunit KorA; sp|O27112|KORA_METTH;evalue=3e-152; PctID=70.81; score=538.
  
 
 0.811
yrdC
Putative isochorismatase family protein YrdC; sp|O07081|YRDC_BACSU;evalue=1e-019; PctID=31.32; score=96.3.
  
 
 0.810
MCBB_0233
Putative ferredoxin MJ0146; sp|Q57610|FER3_METJA;evalue=4e-017; PctID=56.45; score=86.7.
    
 0.808
pycB
Pyruvate carboxylase catalyzes a 2-step reaction,involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. oxaloacetate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Name=Co(2+); Xref=ChEBI:CHEBI:48828; pH dependence: Optimum pH is 8; Temperature dependence: Optimum temperature is 60 degrees Celsius; sp|O27179|PYCB_METTH;evalue=0.0; PctID=71.85; score=837.
    
 0.804
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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