STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_0907Putative protein; tr|F6D239|F6D239_METPW;evalue=0.0; PctID=84.97; score=882; {ECO:0000313|EMBL:AEG17905,1}. (499 aa)    
Predicted Functional Partners:
aqpM
Aquaporin AqpM; Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux (By similarity). three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA); sp|O26206|AQPM_METTH;evalue=2e-094; PctID=70.33; score=345.
  
    0.901
MCBB_0908
Putative conserved protein UCP037465, zinc finger protein, AF1427; tr|F6D240|F6D240_METPW;evalue=2e-030; PctID=81.16; score=137; {ECO:0000313|EMBL:AEG17906,1}.
  
    0.769
pdtaS1
Putative sensor histidine kinase pdtaS; Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR (By similarity). phospho-L-histidine; sp|P9WGL4|PDTAS_MYCTO,sp|P9WGL5|PDTAS_MYCTU; evalue=2e-021; PctID=33.33; score=105.
       0.410
msmS
Heme-binding sensor kinase component part of a two-component regulatory system involved in methyl sulfide metabolism. Does not act as a phytochrome-like photoreceptor. phospho-L-histidine. Name=heme; Xref=ChEBI:CHEBI:30413; Evidence=; Note=Heme-binding is redox-active and coordinates various ligands such as imidazole, dimethyl sulfide, and carbon monoxide depending on the redox state. The redox state of the heme cofactor influences on autophosphorylation activity: while reduced protein does not autophosphorylate, oxidized protein promotes autophosphorylation signal; redox state of heme [...]
       0.410
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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