STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_0921Putative protein; tr|K2RQ00|K2RQ00_METFO;evalue=4e-051; PctID=72.59; score=206; {ECO:0000313|EMBL:EKF84810,1}. (136 aa)    
Predicted Functional Partners:
pdtaR7
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-014; PctID=35.77; score=83.2.
  
  
 0.607
MCBB_0919
Putative esterase AF_2264; sp|O28020|Y2264_ARCFU;evalue=7e-027; PctID=49.15; score=119.
       0.590
MCBB_0920
Hypothetical protein.
       0.581
dfx
Desulfoferrodoxin; Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity (By similarity). oxidized rubredoxin + H(2)O(2). Name=Fe(3+); Xref=ChEBI:CHEBI:29034; Evidence=; Note=Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues; Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence=; Note=Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.; has a [...]
     
 0.552
dnaK
Chaperone protein DnaK; Acts as a chaperone.
  
  
 0.468
ftnA
Bacterial non-heme ferritin; May alleviate iron toxicity in the presence of oxygen. H(+). spherical protein shell (12 +/-1 nM diameter) that can sequester at least 2000 iron atoms. an oxidative environment but not in reduced anaerobic conditions. Is also regulated by oxyR; sp|E1WS50|FTN_BACF6,sp|P0CJ83|FTN_BACFR;evalue=2e-029; PctID=41.25; score=128.
      
 0.461
MCBB_0922
Hypothetical protein.
       0.435
sod
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.434
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.425
MCBB_1186
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.402
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.