STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
MCBB_1072Putative asparagine synthetase [glutamine-hydrolyzing] 1; sp|Q58516|ASNH1_METJA;evalue=5e-060; PctID=44.44; score=232. (516 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.988
lysC
Aspartokinase; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. aspartate. pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4. novo pathway; L-homoserine from L-aspartate: step 1/3. threonine from L-aspartate: step 1/5. regulation) and of a homodimer of 2 isoforms Beta (regulation). Event=Alternative initiation; Named isoforms=2; Name=Alpha; Synonyms=Aspartokinase 2 subunit a [...]
  
 
 0.983
pyrB
Aspartate carbamoyltransferase; sp|O27464|PYRB_METTH;evalue=2e-117; PctID=69.46; score=422.
  
 
 0.982
purB
Adenylosuccinate lyase; sp|O27580|PUR8_METTH;evalue=2e-159; PctID=62.05; score=562; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.976
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
  
 
 0.976
purC
Phosphoribosylaminoimidazole- succinocarboxamidesynthase; sp|O26272|PUR7_METTH;evalue=1e-083; PctID=59.68; score=309; Belongs to the SAICAR synthetase family.
 
 
 0.968
MCBB_1468
Putative aspartate aminotransferase; sp|Q60317|AAT_METJA;evalue=8e-093; PctID=47.59; score=340.
  
 
 0.968
argG
Argininosuccinate synthase; sp|O27322|ASSY_METTH;evalue=1e-170; PctID=72.77; score=599; {ECO:0000255|HAMAP-Rule:MF_00005}; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.968
purM
Phosphoribosylformylglycinamidine cyclo-ligase; sp|A5UM16|PUR5_METS3;evalue=4e-125; PctID=66.96; score=447; {ECO:0000255|HAMAP-Rule:MF_00741}.
 
  
 0.956
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
  
  
 0.954
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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