STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_11564Fe-4S ferredoxin iron-sulfur binding domain-containing protein; tr|F6D4A2|F6D4A2_METPW;evalue=0.0; PctID=77.65; score=855; {ECO:0000313|EMBL:AEG18101,1}. (542 aa)    
Predicted Functional Partners:
mtaC
Methanol-corrinoid protein; Harbors a corrinoid prosthetic group and acts as a methyl group carrier in methanogenesis in the methanol pathway. The methyl group of methanol is first transferred to the corrinoid prosthetic group of MtaC in the cob(I)amide oxidation state. This reaction is mediated by MtaB. The methyl group from MtaC is then transferred to coenzyme M by MtaA. ProRule:PRU00666}; sp|Q46EH4|MTAC_METBF;evalue=2e-046; PctID=39.92; score=186.
 
   
 0.820
mtaA
Methylcobamide:CoM methyltransferase MtaA; Methyltransferase involved in methanogenesis in the methanol pathway. Catalyzes the transfer of the methyl group from the methylated corrinoid protein MtaC to coenzyme M, forming the substrate for coenzyme-B sulfoethylthiotransferase. MtaC can be substituted by free cob(I)alamin in vitro. protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Zn(2+) is involved in coenzyme M activation: in the absence of coenzyme M,zinc is coordinated by a single sulfur ligand an [...]
 
   
 0.743
mtaB
Methanol-corrinoid protein co-methyltransferase; Methyltransferase involved in methanogenesis in the methanol pathway. Catalyzes the methylation of the MtaC-bound cob(I)amide. corrinoid protein] = a [methyl-Co(III) methanol-specific corrinoid protein] + H(2)O; sp|Q46EH3|MTAB_METBF;evalue=7e-116; PctID=47.46; score=417.
     
 0.509
MCBB_0493
Putative methyltransferase MTH_231; sp|O26333|Y231_METTH;evalue=1e-058; PctID=52.12; score=226.
  
     0.449
MCBB_2232
Putative protein MJ0921; sp|Q58331|Y921_METJA;evalue=3e-064; PctID=46.81; score=245.
  
     0.436
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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