STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_1192Universal stress protein MJ0531; sp|Q57951|Y531_METJA;evalue=8e-015; PctID=44.05; score=79.0. (131 aa)    
Predicted Functional Partners:
MCBB_1194
Putative ABC transporter ATP-binding protein MJ1662; sp|Q59056|Y1662_METJA;evalue=7e-145; PctID=46.37; score=514.
  
    0.856
MCBB_1193
Protein MTH_152; sp|O26255|P152_METTH;evalue=1e-053; PctID=52.46; score=209.
     
 0.770
MCBB_1191
DNA-(Apurinic or apyrimidinic site) lyase pyrimidine dimer DNA glycosylase; tr|F6D5S2|F6D5S2_METPW;evalue=3e-046; PctID=61.97; score=190; {ECO:0000313|EMBL:AEG18254,1}.
       0.551
MCBB_0444
Putative signal transduction protein with CBS domains; tr|F6D454|F6D454_METPW;evalue=7e-046; PctID=71.43; score=189; {ECO:0000313|EMBL:AEG17476,1}.
  
  
 0.531
acsA3
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. acetyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; family; sp|A0B8F1|ACSA_METTP;evalue=0.0; PctID=54.31; score=741.
     
 0.524
MCBB_1946
Putative protein; tr|K6T7S9|K6T7S9_9EURY;evalue=2e-019; PctID=76.36; score=100; {ECO:0000313|EMBL:EKQ55848,1}.
   
    0.513
cdhA
Acetyl-CoA decarbonylase/synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
     
 0.500
ogt
Methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine. therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. Rule:MF_00 [...]
  
    0.435
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.