STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. adenosine 5'-phosphate. Name=a metal cation; Xref=ChEBI:CHEBI:25213; Evidence=; Note=Binds 2 metal cations per subunit; family; sp|D5V0N9|CPDA_ARCNC;evalue=5e-010; PctID=31.20; score=65.1; {ECO:0000255|HAMAP-Rule:MF_00905}. (251 aa)    
Predicted Functional Partners:
MCBB_1232
Putative protein; tr|F6D691|F6D691_METPW;evalue=4e-151; PctID=79.77; score=540; {ECO:0000313|EMBL:AEG18304,1}.
 
     0.880
MCBB_1233
Putative protein; tr|F6D692|F6D692_METPW;evalue=0.0; PctID=79.35; score=669; {ECO:0000313|EMBL:AEG18305,1}.
       0.857
tgtA
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.717
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.711
pdtaR7
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-014; PctID=35.77; score=83.2.
 
  
 0.573
pgk2
2-phosphoglycerate kinase; sp|O27911|PGK2_METTH;evalue=3e-128; PctID=81.52; score=457; {ECO:0000255|HAMAP-Rule:MF_00769}.
 
   
 0.500
MCBB_1234
Putative protein; tr|F6D693|F6D693_METPW;evalue=2e-010; PctID=49.25; score=70.9; {ECO:0000313|EMBL:AEG18306,1}.
       0.481
pgk2-2
2-phosphoglycerate kinase; sp|Q58877|PGK2_METJA;evalue=2e-037; PctID=44.34; score=156; {ECO:0000255|HAMAP-Rule:MF_00769}.
  
     0.408
eco57IR
Type IIS restriction enzyme Eco57I; Recognizes the double-stranded sequences CTGAAG and CTTCAG and cleaves respectively 22 bases after C-1 and 14 bases before C'-1. Also acts as a methylase that causes specific methylation on A-5 on one strand, the other strand being methylated by the Eco57IB methylase. specific double-stranded fragments with terminal 5'-phosphates. adenosyl-L-homocysteine + DNA 6-methylaminopurine; sp|P25239|T257_ECOLX;evalue=9e-093; PctID=28.37; score=342.
     
 0.406
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.