STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (336 aa)    
Predicted Functional Partners:
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.999
argB
Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 0.999
argH
Argininosuccinate lyase; sp|Q2NGN7|ARLY_METST;evalue=3e-174; PctID=63.01; score=612; {ECO:0000255|HAMAP-Rule:MF_00006}.
  
 0.999
argG
Argininosuccinate synthase; sp|O27322|ASSY_METTH;evalue=1e-170; PctID=72.77; score=599; {ECO:0000255|HAMAP-Rule:MF_00005}; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
 0.999
argD
Acetylornithine aminotransferase; sp|O27392|ARGD_METTH;evalue=2e-128; PctID=55.78; score=459; {ECO:0000255|HAMAP-Rule:MF_01107}; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.999
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. + L-citrulline. arginine from L-ornithine and carbamoyl phosphate: step 1/3; sp|Q2NI83|OTC_METST;evalue=2e-104; PctID=61.20; score=379; {ECO:0000255|HAMAP-Rule:MF_01109}; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.954
asd-2
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
0.821
carA
Carbamoyl-phosphate synthase small chain; sp|O27079|CARA_METTH;evalue=5e-150; PctID=74.07; score=530; {ECO:0000255|HAMAP-Rule:MF_01209}; Belongs to the CarA family.
  
  
 0.718
nadC
Putative nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
      0.697
MCBB_1238
Flavodoxin; tr|F6D6M9|F6D6M9_METPW;evalue=1e-054; PctID=63.41; score=218; {ECO:0000313|EMBL:AEG18312,1}.
       0.671
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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