STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaP2-2K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. Rule:MF_01075}; Multi-pass membrane protein (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. Rule:MF_01075}; sp|C3LSD1|NHAP2_VIBCM,sp|Q9KNM9|NHAP2_VIBCH; evalue=1e-009; PctID=24.04; score=64.7; {ECO:0000255|HAMAP-Rule:MF_01075}. (400 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.792
MCBB_1764
This is probably a Na(+)/H(+) antiporter. membrane protein (CPA1) transporter (TC 2.A.36) family; sp|Q58671|NAH3_METJA;evalue=4e-017; PctID=23.43; score=89.7.
     
 0.777
nhaP2
K(+)/H(+) antiporter NhaP2; {ECO:0000255|HAMAP-Rule:MF_01075}; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. Rule:MF_01075}; Multi-pass membrane protein (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. Rule:MF_01075}; sp|A7FGZ9|NHAP2_YERP3,sp|B1JHF7|NHAP2_YERPY, sp|B2K787|NHAP2_YERPB, sp|Q669I8|NHAP2_YERPS;evalue=6e-063; PctID=43.97; score=241.
 
   
0.774
trkH
Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA and requires TrkE for transport activity (By similarity). pass membrane protein; sp|Q9L6L2|TRKH_SALTY;evalue=2e-055; PctID=30.98; score=217.
     
 0.707
MCBB_2129
Putative cation transporter MJ1485; sp|Q58880|Y1485_METJA;evalue=7e-085; PctID=37.15; score=315.
     
 0.707
trkA1
Trk system potassium uptake protein TrkA homolog; Part of a potassium transport system. effectors. This is expected to cause a conformation change that regulates potassium transport (By similarity). Sequence=AAB85754.1; Type=Erroneous initiation; Evidence=; sp|O27333|TRKA_METTH;evalue=8e-090; PctID=75.35; score=329.
     
 0.697
trkA3
Trk system potassium uptake protein TrkA homolog; Part of a potassium transport system. effectors. This is expected to cause a conformation change that regulates potassium transport (By similarity). Sequence=AAB85754.1; Type=Erroneous initiation; Evidence=; sp|O27333|TRKA_METTH;evalue=1e-075; PctID=63.43; score=282.
     
 0.697
trkA5
Trk system potassium uptake protein TrkA homolog; Part of a potassium transport system. effectors. This is expected to cause a conformation change that regulates potassium transport (By similarity). Sequence=AAB85754.1; Type=Erroneous initiation; Evidence=; sp|O27333|TRKA_METTH;evalue=1e-083; PctID=70.23; score=308.
     
 0.697
MCBB_1575
Putative MscS family protein slr0639; sp|Q55717|Y639_SYNY3;evalue=3e-022; PctID=30.27; score=105.
     
 0.683
dnaK
Chaperone protein DnaK; Acts as a chaperone.
     
 0.579
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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