STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
MCBB_1332Putative ATP-binding protein MJ0084; sp|Q60392|Y084_METJA;evalue=7e-047; PctID=43.50; score=187. (263 aa)    
Predicted Functional Partners:
cdhC
Acetyl-CoA decarbonylase/synthase complex subunit beta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
  
 0.834
cdhE
Acetyl-CoA decarbonylase/synthase complex subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
 
  
 0.833
cdhD
Acetyl-CoA decarbonylase/synthase complex subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
  
 0.823
MCBB_1331
Putative protein MTH_574; sp|O26674|Y574_METTH;evalue=6e-087; PctID=70.53; score=320.
 
     0.688
hypB
Putative hydrogenase nickel incorporation protein HypB; Could be involved in nickel binding and accumulation. HypB/HupM subfamily; sp|Q57884|HYPB_METJA;evalue=1e-063; PctID=55.66; score=242.
     
 0.676
MCBB_0596
Putative hydrogenase expression/formation protein MJ0200; sp|Q57653|Y200_METJA;evalue=2e-011; PctID=45.71; score=67.8.
     
 0.661
hypF
Putative carbamoyltransferase HypF; Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide (By similarity). ProRule:PRU00518}; sp|Q58123|HYPF_METJA;evalue=0.0; PctID=52.81; score=666.
     
 0.650
tfb
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
      
 0.633
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
      
 0.633
MCBB_2268
Fe-S cluster domain protein; tr|F0T7G7|F0T7G7_METLA;evalue=2e-058; PctID=54.31; score=231; {ECO:0000313|EMBL:ADZ08396,1}.
  
     0.565
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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