STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_1756Putative protein; tr|F6D5U1|F6D5U1_METPW;evalue=1e-069; PctID=54.07; score=269; {ECO:0000313|EMBL:AEG18894,1}. (278 aa)    
Predicted Functional Partners:
hagh
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. glutathione + a 2-hydroxy carboxylate. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 2 Zn(2+) ions per subunit; degradation; (R)-lactate from methylglyoxal: step 2/2. Glyoxalase II family; sp|Q54MR1|GLO2_DICDI;evalue=5e-008; PctID=26.76; score=59.7.
 
  
 0.573
yqhL
Putative protein YqhL; sp|P54510|YQHL_BACSU;evalue=8e-008; PctID=35.53; score=55.8.
 
  
 0.554
pspE
Thiosulfate sulfurtransferase PspE; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient-or energy-limited conditions. PspE catalyzes the sulfur-transfer reaction from thiosulfate to cyanide,to form sulfite and thiocyanate. Also able to use dithiol (dithiothreitol) as an alternate sulfur acceptor. Also possesses a very low mercaptopyruvate sulfurtransferase activity. particularly at low cyanide concentrations (<5 mM). Inhibited by sodium sulfate or sodium chloride at 0.25 M which gives around 50% inhibition of rhodan [...]
  
  
 0.496
cbiX
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
     
 0.465
tarI
Putative ribitol-5-phosphate cytidylyltransferase; Provides activated ribitol phosphate for teichoic acid synthesis. CDP-ribitol. acid biosynthesis; sp|Q8RKI9|TARI_BACPZ;evalue=1e-075; PctID=56.22; score=282.
  
  
 0.460
cysE
Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS). serine. cysteine from L-serine: step 1/2; sp|Q06750|CYSE_BACSU;evalue=1e-060; PctID=57.49; score=233.
  
    0.453
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.452
hcp-2
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.452
yrhO3
Putative protein YrhO; sp|O05405|YRHO_BACSU;evalue=1e-007; PctID=32.97; score=57.0.
  
  
 0.449
MCBB_0010
Putative transcriptional regulator, ModE family; tr|F6D7C1|F6D7C1_METPW;evalue=2e-081; PctID=66.67; score=308; {ECO:0000313|EMBL:AEG17063,1}.
  
    0.417
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.