STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
porAPyruvate synthase subunit PorA; sp|P56810|PORA_METTH;evalue=2e-147; PctID=66.49; score=522. (383 aa)    
Predicted Functional Partners:
porC
Pyruvate synthase subunit PorC; sp|O27772|PORC_METTH;evalue=3e-065; PctID=69.49; score=247.
 
 0.999
porD
Pyruvate synthase subunit PorD; sp|P80903|PORD_METTM;evalue=4e-038; PctID=82.50; score=156.
 
 0.999
porB
Pyruvate synthase subunit PorB; sp|O27771|PORB_METTH;evalue=2e-143; PctID=83.33; score=508.
 0.999
korB
2-oxoglutarate synthase subunit KorB; sp|O27113|KORB_METTH;evalue=8e-118; PctID=68.88; score=423.
 
 0.994
MCBB_1791
Putative ferredoxin MJ0265; sp|Q57713|FER9_METJA;evalue=2e-028; PctID=41.18; score=125.
  
 
 0.994
MCBB_1792
Putative protein MJ0264; sp|Q57712|Y264_METJA;evalue=2e-026; PctID=48.18; score=117.
  
 
 0.994
frhA3
Coenzyme F420 hydrogenase subunit alpha; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen. coenzyme F420. Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408; Note=There are 12-13 Fe atoms/(alpha(1)beta(1)gamma(1)) unit of the FRH; Name=FAD; Xref=ChEBI:CHEBI:57692; subunit family. Sequence=AAB85780.1; Type=Erroneous initiation; Evidence=; sp|P19496|FRHA_METTH;evalue=0.0; PctID=81.28; score=675.
  
  
 0.948
MCBB_0936
Acetate-CoA ligase [ADP-forming] I; Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate. Can use other substrates such as propionyl-CoA and butyryl-CoA, but not phenylacetyl-CoA. Seems to be involved primarily in the conversion of acetyl-CoA to acetate. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. acetyl-CoA. Kinetic parameters: KM=10 uM for acetyl-CoA; KM=7 uM for ADP; KM=110 uM for phosphate; KM=340 uM for acetate; KM=100 uM for phenylacetate; KM=133 uM for ATP; KM=27 uM for CoA; Note=kc [...]
  
 0.947
ydaP
Putative thiamine pyrophosphate-containing protein YdaP; sp|P96591|YDAP_BACSU;evalue=5e-106; PctID=40.30; score=385; Belongs to the TPP enzyme family.
  
 
 0.930
Acsm3
Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q3UNX5-1; Name=2; IsoId=Q3UNX5-2; Sequence=VSP_028397; Note=No experimental confirmation available; Detected in kidney proximal tubules and in liver. Detected at low [...]
  
 
 0.925
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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