STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA-23',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. adenosine 5'-phosphate. Name=a metal cation; Xref=ChEBI:CHEBI:25213; Evidence=; Note=Binds 2 metal cations per subunit; family. Sequence=CAA27241.1; Type=Frameshift; Positions=102; Evidence=; sp|P05675|CPDA_SYNP6;evalue=2e-010; PctID=31.68; score=66.2; {ECO:0000255|HAMAP-Rule:MF_00905}. (268 aa)    
Predicted Functional Partners:
pdtaR7
Putative transcriptional regulatory protein pdtaR; Member of the two-component regulatory system pdtaR/pdtaS. (Potential). ProRule:PRU00308}. Sequence=AAK45932.1; Type=Erroneous initiation; Evidence=; sp|P9WGM2|PDTAR_MYCTO,sp|P9WGM3|PDTAR_MYCTU; evalue=1e-014; PctID=35.77; score=83.2.
 
  
 0.564
pgk2
2-phosphoglycerate kinase; sp|O27911|PGK2_METTH;evalue=3e-128; PctID=81.52; score=457; {ECO:0000255|HAMAP-Rule:MF_00769}.
 
   
 0.508
tgtA
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.446
pgk2-2
2-phosphoglycerate kinase; sp|Q58877|PGK2_METJA;evalue=2e-037; PctID=44.34; score=156; {ECO:0000255|HAMAP-Rule:MF_00769}.
  
     0.416
eco57IR
Type IIS restriction enzyme Eco57I; Recognizes the double-stranded sequences CTGAAG and CTTCAG and cleaves respectively 22 bases after C-1 and 14 bases before C'-1. Also acts as a methylase that causes specific methylation on A-5 on one strand, the other strand being methylated by the Eco57IB methylase. specific double-stranded fragments with terminal 5'-phosphates. adenosyl-L-homocysteine + DNA 6-methylaminopurine; sp|P25239|T257_ECOLX;evalue=9e-093; PctID=28.37; score=342.
     
 0.406
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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