STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifK2This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. + 16 H(2)O = 8 oxidized ferredoxin + H(2) + 2 NH(3) + 16 ADP + 16 phosphate. Name=[8Fe-7S] cluster; Xref=ChEBI:CHEBI:21143; Evidence=; Note=Binds 1 [8Fe-7S] cluster per heterodimer; with the iron protein (nitrogenase component 2); sp|P51754|NIFK_METBA;evalue=2e-071; PctID=37.31; score=270; Belongs to the NifD/NifK/NifE/NifN family. (484 aa)    
Predicted Functional Partners:
nifD
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. + 16 H(2)O = 8 oxidized ferredoxin + H(2) + 2 NH(3) + 16 ADP + 16 phosphate. Name=[8Fe-7S] cluster; Xref=ChEBI:CHEBI:21143; Evidence=; Note=Binds 1 [8Fe-7S] cluster per heterodimer; Name=[7Fe-Mo-9S-C-homocitryl] cluster; Xref=ChEBI:CHEBI:30409; Evidence=; Note=Binds 1 [7Fe-Mo-9S-C-homocitryl] cluster per subunit.; with the iron protein (nitrogenase component 2); sp|Q50788|NIFD_METTM;evalue=0.0; PctID=76.67; score=783.
 
 0.998
nifK
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. + 16 H(2)O = 8 oxidized ferredoxin + H(2) + 2 NH(3) + 16 ADP + 16 phosphate. Name=[8Fe-7S] cluster; Xref=ChEBI:CHEBI:21143; Evidence=; Note=Binds 1 [8Fe-7S] cluster per heterodimer; with the iron protein (nitrogenase component 2) (By similarity); sp|P0CW53|NIFK_METMP;evalue=0.0; PctID=68.19; score=671; Belongs to the NifD/NifK/NifE/NifN family.
 
 
 
0.995
nifH1
Nitrogenase iron protein 1; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
 0.995
nifE
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); sp|P0CW55|NIFE_METMP;evalue=0.0; PctID=62.89; score=646; Belongs to the NifD/NifK/NifE/NifN family.
  
0.991
MCBB_1502
Putative protein MJ1093; sp|Q58493|Y1093_METJA;evalue=7e-080; PctID=53.62; score=297.
  
 0.976
glnBA
Nitrogen fixation nifHD region GlnB-like protein 1; Could be involved in the regulation of nitrogen fixation; sp|P51603|GLNB1_METIV;evalue=1e-040; PctID=76.19; score=164; Belongs to the P(II) protein family.
 
 
 0.973
MCBB_1934
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; tr|A9AB84|A9AB84_METM6;evalue=2e-023; PctID=48.98; score=114; {ECO:0000313|EMBL:ABX02607,1}.
 
  
 0.965
nifH2
Nitrogenase iron protein 2; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
 
 0.954
glnA
Glutamine synthetase; sp|O27612|GLNA_METTH;evalue=0.0; PctID=75.11; score=711; Belongs to the glutamine synthetase family.
   
 
 0.929
nifB
FeMo cofactor biosynthesis protein NifB; Probably involved in the synthesis of the Fe-Mo cofactor. Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence=; Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; sp|P20627|NIFB_NOSS1,sp|Q43883|NIFB_TRIAZ;evalue=4e-011; PctID=40.20; score=66.6.
 
  
 0.907
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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